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METHOD FOR PREPARING GYNOSTEMMA PENTAPHYLLUM EXTRACT WITH INCREASING DAMULIN A AND DAMULIN B CONTENTS, AND PHARMACEUTICAL COMPOSITIONS OF THE SAME FOR TREATING METABOLIC DISEASE

  • US 20110015142A1
  • Filed: 01/29/2010
  • Published: 01/20/2011
  • Est. Priority Date: 07/17/2009
  • Status: Active Grant
First Claim
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1. A method for preparing a novel Gynostemma pentaphyllum extract having increased concentrations of damulin A and damulin B, comprising the step of:

  • treating a concentrate of an ethanol extract of Gynostemma pentaphyllum leaves with a high temperature and/or high pressure reaction for 0.1˜

    24 hours, wherein the temperature is about 40-125°

    C. and the pressure is about 1.2˜

    1100 atmospheres and wherein the increased concentrations of damulin A and damulin B are 0.7-7% (w/w) and 0.5-6% (w/w), respectively, based on the total weight of a dry powder of the novel Gynostemma pentaphyllum extract.

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