METHOD OF TREATING NEUROPATHIC PAIN
First Claim
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1. A method of treating neuropathic pain in a subject, comprising:
- applying a layer of a solid-forming local anesthetic formulation to a skin surface of a human experiencing neuropathic pain, said solid-forming local anesthetic formulation comprising a local anesthetic agent, water, a polymer and being in the state of a semi-solid before being applied to said skin surface; and
maintaining said layer of said formulation on said skin surface for a period of time sufficient to allow said layer of said formulation to transdermally deliver the local anesthetic to the subject and to form a layer of a coherent soft solid after a sufficient amount of water is evaporated from said layer of said formulation,wherein the solid-forming local anesthetic formulation provides relief from said neuropathic pain within about 45 minutes after application to the skin surface.
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Abstract
A method for treating subjects experiencing neuropathic pain is provided. The method involves the application of a solid-forming local anesthetic formulation to a skin surface of the subject experiencing the neuropathic pain and then maintaining the formulation on the skin surface for a period of time sufficient to allow itself to transdermally deliver the local anesthetic to the subject thereby providing relief from the neuropathic pain within about 45 minutes.
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21 Claims
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1. A method of treating neuropathic pain in a subject, comprising:
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applying a layer of a solid-forming local anesthetic formulation to a skin surface of a human experiencing neuropathic pain, said solid-forming local anesthetic formulation comprising a local anesthetic agent, water, a polymer and being in the state of a semi-solid before being applied to said skin surface; and maintaining said layer of said formulation on said skin surface for a period of time sufficient to allow said layer of said formulation to transdermally deliver the local anesthetic to the subject and to form a layer of a coherent soft solid after a sufficient amount of water is evaporated from said layer of said formulation, wherein the solid-forming local anesthetic formulation provides relief from said neuropathic pain within about 45 minutes after application to the skin surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification