Methods and Apparatus for Intraocular Brachytherapy
6 Assignments
0 Petitions
Accused Products
Abstract
Methods and apparatus for intraocular brachytherapy are disclosed in which a cannula is introduced into the eye for delivery of radiation to a target tissue. Techniques for properly locating the cannula with respect to the target tissue, for protecting non-target tissue, for regulating heat generated by x-ray emitters, and for combining therapies are disclosed.
-
Citations
64 Claims
-
1-19. -19. (canceled)
-
20. A method of positioning a first cannula having a distal end for the intraocular delivery of a therapeutic treatment to a target tissue within an eye having a lens so that the distal end of the cannula is in contact with the target tissue comprising:
-
introducing a second cannula into the eye through an access site on the eye, the second cannula having a light source that projects a beam of light toward the target tissue; introducing the first cannula into the eye through a second access site on the eye so that the distal end of the first cannula is between the second cannula and the target tissue within the beam of the light projected toward the target tissue by the second cannula so that a shadow is cast by the distal end of the first cannula that falls on the target tissue, the shadow being observable through the lens of the eye; and advancing the distal end of the first cannula toward the target tissue until the shadow cast by the distal end of the first cannula coincides with the distal end of the first cannula as viewed through the lens, thus indicating contact of the distal end of the first cannula with the target tissue. - View Dependent Claims (58, 59)
-
-
21. A device for local intraocular delivery of a therapeutic treatment to a target tissue comprising:
-
a cannula sized for intraocular insertion into an eye and having a proximal end and a distal end; a therapeutic treatment source adapted to be located in the distal end of the cannula, the source intended to be spaced a predetermined distance from the target tissue for the delivery of the therapeutic treatment; and at least one source of light adapted to project two visible beams of light out of the cannula, the beams of light forming an intersection such that when the intersection is coincident with the target tissue, the treatment source is spaced the predetermined distance from the target tissue. - View Dependent Claims (22, 23, 60, 61, 62)
-
-
24-37. -37. (canceled)
-
38. A device for local intraocular delivery of radiation to a target tissue comprising:
-
a probe sized for insertion into an eye and having a proximal end and a distal end; a radiation-emitting source having a predetermined length adapted to be located in the distal end of the probe, the radiation-emitting source having a proximal end and a distal end; and a filter associated with the distal end of the probe that blocks a greater amount of radiation at the distal end of the radiation-emitting source than at the proximal end of the radiation-emitting source so that a generally-symmetrical dose profile is delivered to the target tissue by the radiation emitting source when the distal end of the probe is orientated at an angle with respect to a plane defined generally by the target tissue. - View Dependent Claims (63, 64)
-
-
39-57. -57. (canceled)
Specification