POROUS MEMBRANES FOR MEDICAL IMPLANTS AND METHODS OF MANUFACTURE
First Claim
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1. A single-layer porous membrane for use in medical implants comprising:
- an elongated fiber having a width of 5 to 500 micrometers, the elongated fiber forming a plurality of non-crossing traces extending adjacently from a first end to a second end of the membrane, each trace contacting its adjacent traces in an alternating manner, adjacent traces being bonded together at points of contact, the traces defining a plurality of pores of predetermined sizes.
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Abstract
The present invention involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.
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Citations
26 Claims
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1. A single-layer porous membrane for use in medical implants comprising:
an elongated fiber having a width of 5 to 500 micrometers, the elongated fiber forming a plurality of non-crossing traces extending adjacently from a first end to a second end of the membrane, each trace contacting its adjacent traces in an alternating manner, adjacent traces being bonded together at points of contact, the traces defining a plurality of pores of predetermined sizes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A single-layer porous membrane for use with medical implants comprising:
a continuous elongated fiber having a width of 5 to 500 micrometers forming a predetermined pattern of non-crossing traces, the traces extending adjacently from a first end to a second end of the membrane, each trace being bonded at contact portions to its adjacent traces, the contact portions being spaced apart, the traces defining a plurality of pores of predetermined sizes, the membrane having a thickness approximately equal to the thickness of the fiber. - View Dependent Claims (18, 19, 20)
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21. An implantable medical device comprising:
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a medical implant; a single-layer porous membrane coupled to the medical implant, the single-layer porous membrane comprising; an elongated fiber of bio-compatible material having a width of 5 to 500 micrometers, the elongated fiber forming a plurality of non-crossing traces extending adjacently from a first end to a second end of the membrane, each trace contacting its adjacent traces in an alternating manner, adjacent traces being bonded together at points of contact, the traces defining a plurality of pores of predetermined sizes. - View Dependent Claims (22, 23, 24, 25, 26)
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Specification