DRUG DELIVERY SYSTEM FOR PHARMACEUTICALS AND RADIATION
3 Assignments
0 Petitions
Accused Products
Abstract
The present invention provides a drug delivery system for delivery of an agent and a radiopharmaceutical agent. The drug delivery system may specifically target an organ, tissue, cells, extracellular matrix, or intracellular compartment. Typically, the drug delivery system is a particle. Pharmaceutical compositions comprising the inventive particles are also provided. The present invention provides methods of preparing and using the inventive particles and pharmaceutical compositions. The inventive particles are useful in treating and diagnosing a variety of diseases including cancer. The inventive particles are also useful in tracking particles in vivo.
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Citations
77 Claims
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1-8. -8. (canceled)
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9. A particle comprising:
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a polymeric core comprising a chemotherapeutic agent; and an outer lipid monolayer comprising a chelator and a radiopharmaceutical agent. - View Dependent Claims (10, 58, 64, 74, 76)
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11. (canceled)
- 12. A particle comprising an agent and a radiopharmaceutical agent, wherein at least one of the agents is encapsulated in a polymeric matrix.
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14-16. -16. (canceled)
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18-25. -25. (canceled)
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28-31. -31. (canceled)
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36-38. -38. (canceled)
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42. (canceled)
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44-45. -45. (canceled)
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47-57. -57. (canceled)
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59-63. -63. (canceled)
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65-73. -73. (canceled)
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75. (canceled)
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77-82. -82. (canceled)
Specification