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Device including altered microorganisms, and methods and systems of use

  • US 20110027181A1
  • Filed: 05/28/2010
  • Published: 02/03/2011
  • Est. Priority Date: 12/14/2005
  • Status: Active Grant
First Claim
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1. A device, comprising:

  • at least one semi-permeable barrier substantially enclosing at least one auxotrophic microorganism, the at least one auxotrophic microorganism including at least one nucleic acid construct encoding at least one therapeutic agent, the barrier defining an interior region and exterior region; and

    wherein the device includes at least one metabolite required by the at least one auxotrophic microorganism.

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