Herbal enhanced analgesic formulations

• US 20110028412A1
• Filed: 08/03/2010
• Published: 02/03/2011
• Est. Priority Date: 08/03/2009
• Status: Abandoned Application

• Current Assignee: Cappello, Inc.
• Original Assignee: Cappellos, Inc.
• Inventors: Durst, Lawrence, Cappello, John V.
• Application Number:
  US12/804,972
• Publication Number:
  US 20110028412A1
• Time in Patent Office: Days
• US Class Current: 514/25
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/375 Ascorbic acid, i.e. vitamin C; Salts thereof
• CPC Class Codes: A61K 31/405 Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
• CPC Class Codes: A61K 31/4415 Pyridoxine, i.e. Vitamin B6 pyridoxal phosphate A61K31/675
• CPC Class Codes: A61K 31/455 Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
• CPC Class Codes: A61K 31/7004 Monosaccharides having only carbon, hydrogen and oxygen atoms
• CPC Class Codes: A61K 31/7034 attached to a carbocyclic compound, e.g. phloridzin
• CPC Class Codes: A61K 33/30 Zinc; Compounds thereof
• CPC Class Codes: A61K 36/76 Salicaceae (Willow family), e.g. poplar
• CPC Class Codes: A61P 25/04 Centrally acting analgesics, e.g. opioids

Abstract

The analgesic properties of L-tryptophan and 5-HTP can be safely enhanced with the coadministration of salacin. Salacin can be effectively provided in the form of white willow bark along with other ingredients to further enhance the formulation'"'"'s analgesic effect. As salacin can cause the loss of vitamin C in humans, the formulation advantageously includes a supplemental amount of vitamin C.

Claims

1. A analgesic formulation comprising:

salacin;

at least one of L-tryptophan and 5-HTP;

niacinamide;

pyridoxine;

fructose; and

vitamin C.

2. The formulation of claim 1, wherein said salicin is provided in the form of at least one of white willow bark and extracts of white willow bark.

3. The formulation of claim 1, wherein said salicin comprises up to about 500 mg of salacin.

4. The formulation of claim 1, wherein said at least one of said L-tryptophan and 5-HTP comprises up to about 250 mg of said at least one of said L-tryptophan and 5-HTP.

5. The formulation of claim 1, wherein said niacinamide comprises up to about 25 mg of at least one of niacin and nicotinamide.

6. The formulation of claim 1, wherein said pyridoxine comprises up to about 25 mg of pyridoxine.

7. The formulation of claim 1, wherein said fructore comprises up to about 25 mg of fructose.

8. The formulation of claim 1, wherein said vitamin C comprises up to about 100 mg. of vitamin C.

9. The formulation of claim 1, further comprising zinc.

10. An analgesic formulation, comprising:

up to about 500 mg salacin;

up to about 250 mg L-tryptophan;

up to about 25 mg niacinamide;

up to about 25 mg pyridoxine;

up to about 25 mg fructose; and

up to about 500 mg vitamin C.

11. The formulation of claim 10, further comprising up to 24 mg of zinc.

12. The formulation of claim 10, wherein said salacin comprises about 250 mg of salacin.

13. The formulation of claim 10, wherein said salacin is provided in the form of white willow bark.

14. The formulation of claim 10, wherein said L-tryptophan comprises about 100 mg of L-tryptophan.

15. The formulation of claim 10, wherein said niacinamide comprises about 10 mg of niacin.

16. The formulation of claim 10, wherein said fructose comprises about 25 mg of fructose.

17. The formulation of claim 10, wherein said vitamin C comprises about 100 mg of vitamin C.

18. The formulation of claim 11, wherein said zinc is provided in the form of about 100 mg of zinc gluconate.

19. A method of relieving pain in a human, comprising:

orally administering to the human a formulation comprising salacin, at least one of L-tryptophan and 5-HTP, niacinamide, pyridoxine, fructose and vitamin C.

20. The method of claim 19, wherein said salacin is administered in the form of at least one of white willow bark and extracts of white willow bark.