METHOD FOR SPECTROPHOTOMETRIC BLOOD OXYGENATION MONITORING

• US 20110028812A1
• Filed: 08/06/2010
• Published: 02/03/2011
• Est. Priority Date: 02/08/2008
• Status: Abandoned Application

• Current Assignee: Cas Medical Systems Incorporated (Edwards Lifesciences Corporation)
• Original Assignee: Cas Medical Systems Incorporated (Edwards Lifesciences Corporation)
• Inventors: Benni, Paul
• Application Number:
  US12/851,977
• Publication Number:
  US 20110028812A1
• Time in Patent Office: Days
• US Class Current: 600/323
• CPC Class Codes: A61B 5/14553 specially adapted for cerebral tissue
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes

Abstract

A method and apparatus for non-invasively determining a blood oxygenation level within a subject'"'"'s tissue is provided. The method includes the steps of: a) providing a spectrophotometric sensor operable to transmit light into the subject'"'"'s tissue, and to sense the light; b) inputting into the sensor at least one of the subject'"'"'s age, weight, brain development, and head size; c) spectrophotometrically sensing the subject'"'"'s tissue along a plurality of wavelengths using the sensor, and producing signal data from sensing the subject'"'"'s tissue; and d) processing the signal data utilizing the at least one of the subject'"'"'s age, weight, brain development, and head size, to determine the blood oxygen saturation level within the subject'"'"'s tissue using a difference in attenuation between the wavelengths.

Claims

1. A method for non-invasively determining a blood oxygenation level within a subject'"'"'s tissue, comprising the steps of:

providing a spectrophotometric sensor operable to transmit light into the subject'"'"'s tissue, and to sense the light;

inputting into the sensor at least one of the subject'"'"'s age, weight, brain development, and head size;

spectrophotometrically sensing the subject'"'"'s tissue along a plurality of wavelengths using the sensor, and producing signal data from sensing the subject'"'"'s tissue; and

processing the signal data utilizing the at least one of the subject'"'"'s age, weight, brain development, and head size, to determine the blood oxygen saturation level within the subject'"'"'s tissue using a difference in attenuation between the wavelengths.

2. The method of claim 1, wherein the sensor includes a processor that is adapted to include one or more calibration constants that relate to subject age, weight, brain development, and head size.

3. The method of claim 2, wherein the processor is adapted to utilize one or more of a graph, a database structure, and a mathematical relationship to relate the one or more calibration constants to subject age, weight, brain development, and head size.

4. The method of claim 3, wherein the one or more of a graph, a database structure, and a mathematical relationship are based on empirically collected data.

5. An apparatus for non-invasively determining a blood oxygenation level within a subject'"'"'s tissue, comprising:

a sensor having one or more transducer portions and a processor portion;

wherein each of the one or more transducer portions includes at least one light source and at least one light detector, and the light source is operable to transmit light along a plurality of wavelengths into the subject'"'"'s tissue, and the light detector is operable to detect light along the wavelengths traveling through the subject'"'"'s tissue, and each of the transducer portions is operable to produce signal data representative of the light sensed within the subject'"'"'s tissue; and

wherein the processor portion is operably connected to the one or more transducer portions, and is adapted to receive input of at least one of the subject'"'"'s age, weight, brain development, and head size, and the processor portion is adapted to process the signal data utilizing at least one of the subject'"'"'s age, weight, brain development, and head size, to determine the blood oxygen saturation level within the subject'"'"'s tissue using a difference in attenuation between the wavelengths.

6. The apparatus of claim 5, wherein the processor portion is adapted to include one or more calibration constants that relate to a subject age, weight, brain development, and head size.

7. The apparatus of claim 6, wherein the processor is adapted to utilize one or more of a graph, a database structure, and a mathematical relationship to relate the one or more calibration constants to a subject age, weight, brain development, and head size.

8. The apparatus of claim 7, wherein the one or more of a graph, a database structure, and a mathematical relationship are based on empirically collected data.

9. The apparatus of claim 5, wherein at least one of the transducer portions includes a housing to which the at least one light source and the at least one light detector are mounted and which housing has a lengthwise extending centerline and a deflection sensor adapted to sense flexure of the housing relative to the lengthwise extending centerline;

and

wherein the processor portion is adapted to receive input from the deflection sensor and is adapted to process the signal data utilizing the deflection sensor input.

10. A method for non-invasively determining a blood oxygenation level within a subject'"'"'s tissue, comprising the steps of:

providing a spectrophotometric sensor having one or more transducer portions and a processor portion, which transducer portions are operable to transmit light into the subject'"'"'s tissue and sense light passing through the subject'"'"'s tissue, and at least one of which transducer portions includes a housing having a lengthwise extending centerline and a deflection sensor adapted to sense flexure of the housing relative to the lengthwise extending centerline;

spectrophotometrically sensing the subject'"'"'s tissue along a plurality of wavelengths using the transducer portions, and producing signal data from sensing the subject'"'"'s tissue; and

processing the signal data, including using input from the deflection sensor to determine flexure of the at least one transducer portion, to determine the blood oxygen saturation level within the subject'"'"'s tissue.

11. The method of claim 10, wherein the input from the deflection sensor is related to a physical characteristic of the subject during the processing of the signal data.

12. The method of claim 11, wherein the processing includes relating the input from the deflection sensor to at least one of a subject head size and subject head geometry.