Biosensor Having Improved Hematocrit and Oxygen Biases
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Abstract
The present invention provides reagent compositions, and analyte measuring devices and methods that utilize the reagent compositions.
34 Citations
95 Claims
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1-65. -65. (canceled)
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66. A reagent composition, comprising:
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a mediator, wherein the mediator is 1,10-phenanthroline-5,6-dione or a derivative thereof; at least one magnesium ion; and at least one counter anion. - View Dependent Claims (67, 68, 69, 70, 71, 72, 73)
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74. A biosensor comprising:
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an electrode support; a working electrode disposed on the electrode support; a reference electrode disposed on the electrode support; and a reagent composition deposited over the working electrode and the reference electrode, wherein the reagent composition comprises an enzyme, a mediator, a magnesium ion, and a counter anion, wherein the mediator is 1,10-phenanthroline-5,6-dione or a derivative thereof. - View Dependent Claims (75, 76, 77, 78, 79, 80, 81, 82, 83, 84)
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85. A method for determining the concentration of an analyte in a sample of biological fluid, the method comprising the steps of:
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inserting a biosensor into an analyte monitor, the biosensor comprising; an electrode support having at least one electrode thereon; and a reagent composition disposed on the at least one electrode, the reagent composition comprising; an enzyme; a mediator, wherein the mediator is 1,10-phenanthroline-5,6-dione or a derivative thereof; a magnesium ion; and a counter anion; applying the biological fluid to the biosensor; applying a voltage at the electrode; measuring the current at the electrode; and correlating the current measured to the concentration of the analyte. - View Dependent Claims (86, 87, 88, 89, 90, 91, 92, 93, 94, 95)
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Specification