BIOFUNCTIONALIZED QUANTUM DOTS FOR BIOLOGICAL IMAGING
First Claim
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1. A biofunctionalized quantum dot, comprising:
- a nanocrystalline core exhibiting quantum confinement and having a band gap and a surface;
a mercaptoalkanoic acid linked to the surface; and
a biofunctional group linked to the surface,wherein the biofunctional group comprises a saccharide or the mercaptoalkanoic acid is linked to the surface of the nanocrystalline core without a shell layer.
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Abstract
Novel biofunctionalized quantum dots include a mercaptoalkanoic acid linked to the surface of a nanocrystalline core and a biofunctional group linked to the surface. Biofunctionalized quantum dots are made by a novel synthesis method. Biofunctionalized quantum dots can be used in imaging or therapy applications.
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Citations
11 Claims
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1. A biofunctionalized quantum dot, comprising:
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a nanocrystalline core exhibiting quantum confinement and having a band gap and a surface; a mercaptoalkanoic acid linked to the surface; and a biofunctional group linked to the surface, wherein the biofunctional group comprises a saccharide or the mercaptoalkanoic acid is linked to the surface of the nanocrystalline core without a shell layer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification