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FLUOROGENIC PEPTIDES AND THEIR METHOD OF PRODUCTION

  • US 20110039289A1
  • Filed: 03/14/2008
  • Published: 02/17/2011
  • Est. Priority Date: 03/14/2008
  • Status: Abandoned Application
First Claim
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1. A method of making a fluorogenic peptide with an acridone fluorophor, the method comprising the steps of:

  • (a) providing an acridone derivative, said acridone derivative having first and second reactive groups (or precursors thereof),(b) providing a solid phase support provided with reactive species for reacting with the first reactive group of the acridone derivative(c) causing the solid phase support and acridone derivative to react so that the acridone derivative is attached to the solid phase support(d) providing the peptide or reagents for the formation of the peptide, and(e) subsequent to step (c), causing the reaction of the second acridone reactive group with the peptide or one or more of the reagents for the formation of the peptide.

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