Multi-Modal Drug Delivery System
First Claim
Patent Images
1. A device for the transdermal delivery of a therapeutic agent at a treatment site comprising a housing containing:
- a mechanical vibration element;
a light source;
a heating and/or cooling element;
a power source for powering said mechanical vibrational element, light source, and heating and/or cooling clement; and
an electronic control module for controlling said mechanical vibrational element, light source, and heating and/or cooling element.
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Abstract
A device for the transdermal delivery of a therapeutic agent at a treatment site comprising a housing containing: a mechanical vibration element; a light source; a heating and/or cooling clement; a power source for powering said mechanical vibrational element, light source, and heating element; and an electronic control module.
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Citations
91 Claims
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1. A device for the transdermal delivery of a therapeutic agent at a treatment site comprising a housing containing:
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a mechanical vibration element; a light source; a heating and/or cooling element; a power source for powering said mechanical vibrational element, light source, and heating and/or cooling clement; and an electronic control module for controlling said mechanical vibrational element, light source, and heating and/or cooling element. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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32. A method for transdermally delivering a therapeutic agent to a patient'"'"'s treatment site comprising:
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(a) decreasing the temperature of the treatment site by cooling the treatment site; (b) applying mechanical energy the treatment site, said mechanical energy having a frequency of about 15 kHz to 100 kHz; (c) applying light energy to said treatment site; and (d) applying a composition comprising a therapeutically effective amount of said therapeutic agent. - View Dependent Claims (33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
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52. A method for transdermally delivering a therapeutic agent to a patient'"'"'s treatment site comprising:
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(a) increasing the temperature of the treatment site by heating the treatment site by about 0.5 to 2°
C.;(b) applying mechanical energy the treatment site, said mechanical energy a frequency of 15 kHz to 100 kHz; (c) applying light energy to said treatment site; and (d) applying a composition comprising a therapeutically effective amount of said therapeutic agent to the treatment site. - View Dependent Claims (53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71)
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72. A method for transdermally delivering a therapeutic agent to a patient'"'"'s treatment site comprising:
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(a) increasing the temperature of the treatment site by heating the treatment site by about 2 to 4°
C.;(b) applying mechanical energy the treatment site, said mechanical energy a frequency of about 15 kHz to 100 kHz; (c) applying light energy to said treatment site; and (d) applying a composition comprising a therapeutically effective amount of said therapeutic agent to the treatment site. - View Dependent Claims (73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91)
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Specification