METHODS AND IMPLANTABLE DEVICES FOR TREATING SUPRAVENTRICULAR ARRHYTHMIAS
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Abstract
A medication, method and device for cardiac treatment are provided, in particular, for treating supraventricular arrhythmias. Specifically, a method is provided for treating supraventricular arrhythmias, using a therapeutically effective amount of a cholinergic receptor agonist, for example, acetylcholine. This device may be part of universal device which provides pacing and defibrillation. In particular, the present invention can be used to treat atrial fibrillation, atrial flutter and atrial tachycardia by a bolus injection of a rapidly hydrolysable cholinergic receptor agonist such as acetylcholine.
48 Citations
74 Claims
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1-53. -53. (canceled)
- 54. A device comprising a device body adapted for implantation into a body and a sensor for sensing an electrical or mechanical activity of a heart being in contact with said device body when implanted into the body, said device body housing a reservoir for holding a cholinergic receptor agonist suitable for intracardiac or and/or intravascular administration via a vein, or an artery or a heart chamber.
- 65. A device comprising a device body adapted for implantation into a body, said device body housing a reservoir for holding a cholinergic receptor agonist for administering into or close to a heart tissue.
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74. An implantable cardiac treatment device, comprising a reservoir containing a cholinergic receptor agonist and a releasing mechanism for releasing a predetermined dose of said cholinergic receptor agonist in, on or in proximity to a heart further comprising a sensor for sensing supraventricular arrhythmia of said heart further wherein said sensor communicates with said releasing mechanism for releasing said predetermined dose of said cholinergic receptor agonist in, on or in proximity to said heart when said supraventricular arrhythmia of said heart is sensed by said sensor further wherein decision to release said predetermined dose of said cholinergic receptor agonist is determined by application of an algorithm residing on a micro chip associated with said device.
Specification