MASKED INTRAOCULAR IMPLANTS AND LENSES

• US 20110040376A1
• Filed: 08/13/2010
• Published: 02/17/2011
• Est. Priority Date: 08/13/2009
• Status: Active Grant

• Current Assignee: Healthcare Royalty Partners II LP (Toronto-Dominion Bank)
• Original Assignee: Acufocus, Inc.
• Inventors: Kosmynine, Alexei N., Christie, Bruce A.
• Granted Patent: US 9,492,272 B2
• Time in Patent Office: Days
• US Class Current: 623/6.17
• CPC Class Codes: A61F 2/15 Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
• CPC Class Codes: A61F 2/16 Intraocular lenses
• CPC Class Codes: A61F 2/1613 having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
• CPC Class Codes: A61F 2/1659 having variable absorption coefficient for electromagnetic radiation, e.g. photochromic lenses
• CPC Class Codes: A61F 2002/1681 having supporting structure for lens, e.g. haptics
• CPC Class Codes: A61F 2002/1696 Having structure for blocking or reducing amount of light transmitted, e.g. glare reduction
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures
• CPC Class Codes: A61F 2240/002 Designing or making customized prostheses
• CPC Class Codes: A61F 2250/0053 differing in optical properties
• CPC Class Codes: A61F 2250/0058 Additional features; Implant or prostheses properties not otherwise provided for
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: B29D 11/00317 Production of lenses with markings or patterns
• CPC Class Codes: B29D 11/023 Implants for natural eyes
• CPC Class Codes: B29K 2033/04 Polymers of esters
• CPC Class Codes: B29K 2105/0085 Copolymers

Abstract

Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Claims

1. An intraocular device comprising:

a lens body comprising a surface with a transition zone, the transition zone configured to reduce a thickness of the lens body along an optical axis of the lens body; and

a mask configured to block a substantial portion of optical aberrations that would be created by light passing through the transition zone.

2. The intraocular device of claim 1, wherein the surface is a posterior surface of the lens body.

3. The intraocular device of claim 1, wherein the surface is an anterior surface of the lens body.

4. The intraocular device of claim 1, wherein an inner portion of the surface is convex, the transition zone is concave and an outer portion of the surface is convex, wherein the transition zone is adjacent the inner portion and the outer portion.

5. The intraocular device of claim 1, wherein an inner portion and an outer portion of the surface have a positive optical power, and the transition zone is adjacent the inner portion and the outer portion.

6. The intraocular device of claim 1, wherein an inner portion and an outer portion of the surface have a negative optical power, and the transition zone is adjacent the inner portion and the outer portion.

7. The intraocular device of claim 1, wherein the surface comprises an inner portion and an outer portion, and an outer perimeter of the inner portion is surrounded by an inner perimeter of the transition zone.

8. The intraocular device of claim 7, wherein an outer perimeter of the transition zone is surrounded by an inner perimeter of the outer portion.

9. The intraocular device of claim 1, wherein the surface comprises an inner portion and an outer portion, and a maximum thickness of the lens body in a region of the inner portion is less than the maximum thickness of the lens body in a region of the transition zone.

10. The intraocular device of claim 1, wherein the mask is attached to the surface.

11. The intraocular device of claim 1, wherein the mask is between the surface and a second surface of the lens body.

12. The intraocular device of claim 1, wherein the mask comprises an aperture and an opaque region adjacent the aperture.

13. The intraocular device of claim 12, wherein the aperture comprises a diameter of about 0.85 mm to about 1.8 mm.

14. The intraocular device of claim 13, wherein the mask comprises an outer diameter of about 3 mm to about 5 mm.

15. The intraocular device of claim 1, wherein the mask increases depth of focus of a patient.

16. The intraocular device of claim 1, further comprising a haptic attached to the lens body to prevent the intraocular device from moving after being implanted within an eye.

17. The intraocular device of claim 1, wherein the mask comprises a plurality of holes characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.

18. The intraocular device of claim 1, further comprising a support member coupled to the mask and extending from the mask to an outer surface of the lens body.

19. The intraocular device of claim 18, wherein the mask comprises a plurality of holes characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.

20. The intraocular device of claim 19, wherein the support member comprises a plurality of holes characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.

21. The intraocular device of claim 1, further comprising haptics coupled to the mask.

22. An intraocular device comprising:

a lens body comprising a first surface and a second surface, the first surface comprises a first portion, a second portion and a third portion, an optic axis of the lens body passes through the first portion, and the second portion is between the first portion and the third portion;

a mask positioned between the second surface and the second portion of the first surface; and

wherein a distance from the first portion neighboring the second portion to a plane perpendicular to the optic axis and tangent to the second surface comprises a first distance, and a distance from the third portion neighboring the second portion to the plane perpendicular to the optic axis and tangent to the second surface comprises a second distance greater than the first distance.

23. A method for improving the vision of a patient, the method comprising:

providing an intraocular device comprising a lens body comprising a surface with a transition zone, the transition zone configured to reduce a thickness of the lens body along an optic axis of the lens body, and the intraocular device further comprising a mask configured to block a substantial portion of optical aberrations that would be created by light passing through the transition zone; and

inserting the intraocular device into an intraocular space of an eye.