TOOL FOR ACCURATE QUANTIFICATION IN MOLECULAR MRI
First Claim
1. A method for providing an image from complex energy signals collected from an object, the method including:
- collecting the complex energy signals from the object, where each of the complex energy signals includes phase and magnitude components;
providing additional information of characteristics of the object, wherein the additional information is independent from the phase components; and
generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics.
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0 Petitions
Accused Products
Abstract
A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.
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Citations
129 Claims
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1. A method for providing an image from complex energy signals collected from an object, the method including:
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collecting the complex energy signals from the object, where each of the complex energy signals includes phase and magnitude components; providing additional information of characteristics of the object, wherein the additional information is independent from the phase components; and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics. - View Dependent Claims (2, 3, 4, 9, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 27, 84, 85)
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5-8. -8. (canceled)
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10. (canceled)
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26. (canceled)
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28-83. -83. (canceled)
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86-92. -92. (canceled)
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92. A method for providing magnetic source magnetic resonance imaging using a magnetic resonance system based on an inversion operation describing a relationship between field and source signals, the method including:
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collecting magnetic resonance signals from an object having a susceptibility distribution, wherein the magnetic resonance signals have phase and magnitude components; improving a condition of the inversion operation based on additional information of the object, wherein the additional information of the object is independent from the phase components of the magnetic resonance signals; and generating an image of the object by utilizing the magnetic resonance signals and the t inversion operation, wherein the image represents a quantitative estimation of the susceptibility distribution. - View Dependent Claims (99)
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93-98. -98. (canceled)
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100. One or more computer readable media storing computer executable code for instructing one or more digital processors to provide magnetic source magnetic resonance imaging, the computer executable code including:
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instructions for collecting magnetic resonance signals emitted by an object having a susceptibility distribution, wherein each of the magnetic resonance signals has phase and magnitude components; and instructions for generating an image of the object from the magnetic resonance signals and additional information describing a relationship between field and source signals for the object, where the additional information is independent from the phase components of the collected magnetic resonance signals and the image represents a quantitative estimation of the susceptibility distribution. - View Dependent Claims (101, 102, 103, 104, 105, 106, 107, 108, 109)
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110-119. -119. (canceled)
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120. A display device for displaying a magnetic source magnetic resonance image including:
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a display area for displaying an image of a susceptibility distribution of an object; and means for visualizing a quantitative attribute of the image of the susceptibility distribution of the object, wherein the quantitative attribute is based on magnetic resonance signals collected from the object and additional information about the susceptibility distribution. - View Dependent Claims (121, 122, 123, 124)
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125. A method for providing an image from signals collected from an object, the method including:
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collecting signals from the object, wherein the signal include phase and magnitude components; generating intermediate data from the collected signals; providing additional information of characteristics of the object, wherein the additional information is independent form the phase components of the signals; and generating the image to include a quantitative estimation of characteristic of the object based on the intermediate data and the additional information. - View Dependent Claims (126, 127, 128)
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129-132. -132. (canceled)
Specification