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METHODS FOR PREDICTING THE EFFICACY OF TREATMENT

  • US 20110045480A1
  • Filed: 08/19/2010
  • Published: 02/24/2011
  • Est. Priority Date: 08/19/2009
  • Status: Active Grant
First Claim
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1. A method for predicting the efficacy of treatment of breast cancer comprising:

  • analyzing an expression profile of marker genes from a cancerous breast tissue; and

    predicting the efficacy of treatment if the expression profile from the cancerous breast tissue matches a predetermined expression profile that indicates a patient will respond to the treatment wherein the marker gene is selected from a group consisting of ASPM, NCAPG, CDKN3, AURKA, FOXM1, CEP55, TNFRSF6B, FGFBP1, CAPRIN2, TUBG1, ZWILCH, RRM2, ACTB, ACTN1, EPHA2, TRIP13, CKS2, VRK1, DUSP4, EIF4A1, SERPINE2, ODC1 and combinations thereof.

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