COMBINATION ANALGESIC OPIOID PAIN THERAPY
First Claim
1. An analgesic pharmaceutical composition comprising morphine and oxycodone, or pharmaceutically acceptable salts thereof, in a ratio of from about 3 to 2 to about 1.25 to 1, morphine to oxycodone by weight, optionally in combination with a pharmaceutically acceptable carrier, wherein the morphine and oxycodone are each present in analgesic amounts.
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Accused Products
Abstract
Provided are pharmaceutical compositions and methods for the alleviation of pain in a patient with ratios of morphine and oxycodone that provide lower incidence of adverse side effects compared to equi-analgesic doses of morphine and oxycodone alone. The pharmaceutical compositions comprise an analgesic amount of morphine and an analgesic amount of oxycodone, or pharmaceutically acceptable salts thereof, in ratios of about 3 to 2 to about 1.25 to 1, morphine to oxycodone by weight.
13 Citations
18 Claims
- 1. An analgesic pharmaceutical composition comprising morphine and oxycodone, or pharmaceutically acceptable salts thereof, in a ratio of from about 3 to 2 to about 1.25 to 1, morphine to oxycodone by weight, optionally in combination with a pharmaceutically acceptable carrier, wherein the morphine and oxycodone are each present in analgesic amounts.
- 13. A method for the alleviation of pain in a patient comprising administering to the patient a pharmaceutical composition comprising morphine and oxycodone, or pharmaceutically acceptable salts thereof, in a ratio of from about 3 to 2 to about 1.25 to 1, morphine to oxycodone by weight, optionally in combination with a pharmaceutically acceptable carrier, wherein the morphine and oxycodone are each present in analgesic amounts.
Specification