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METHODS FOR CONCOMITANT ADMINISTRATION OF COLCHICINE AND A SECOND ACTIVE AGENT

  • US 20110046227A1
  • Filed: 08/21/2009
  • Published: 02/24/2011
  • Est. Priority Date: 08/21/2009
  • Status: Abandoned Application
First Claim
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1. A method of treating a patient with colchicine, comprisingorally administering an adjusted daily dosage amount of colchicine to the patient who is receiving concomitant administration of a daily dose of atorvastatin, wherein the atorvastatin is administered to treat an atorvastatin-responsive condition,wherein the adjusted daily dosage amount of colchicine is about 50% to 75% of an intended daily dosage amount of colchicine, andwherein the intended daily dosage amount of colchicine is a daily dosage amount suitable for the patient if the patient were not receiving concomitant atorvastatin, wherein concomitant administration of atorvastatin is administration either simultaneously with colchicine or within a time period during which the effects of the colchicine are still operative in the patient.

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