ENA NUCLEIC ACID DRUGS MODIFYING SPLICING IN mRNA PRECURSOR
First Claim
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1. An oligonucleotide having the nucleotide sequence as shown in any one of SEQ ID NOS:
- 2-6, 10-22, 30-78, 87 or 88 in the SEQUENCE LISTING, or a pharmacologically acceptable salt thereof.
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Abstract
Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.
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Citations
1 Claim
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1. An oligonucleotide having the nucleotide sequence as shown in any one of SEQ ID NOS:
- 2-6, 10-22, 30-78, 87 or 88 in the SEQUENCE LISTING, or a pharmacologically acceptable salt thereof.
Specification