DIALYSIS TREATMENT DEVICES FOR REMOVING UREA

• US 20110048949A1
• Filed: 08/27/2009
• Published: 03/03/2011
• Est. Priority Date: 08/27/2009
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Lo, Ying-Cheng, Ding, Yuanpang Samuel
• Granted Patent: US 8,404,091 B2
• Time in Patent Office: Days
• US Class Current: 204/543
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2209/088 on the body

Abstract

Dialysis treatment devices and methods for removing urea from dialysis waste streams are provided. In a general embodiment, the present disclosure provides a dialysis treatment device including a first cell having a first electrodialysis unit, a second cell having at least one of a urease compartment and a sorbent compartment and in fluid communication with the first cell, and a third cell having a second electrodialysis unit and in fluid communication with the second cell.

Claims

1. A dialysis fluid treatment device comprising:

a first cell comprising a first electrodialysis unit;

a second cell comprising at least one of a urease compartment and a sorbent compartment and in fluid communication with the first cell; and

a third cell comprising a second electrodialysis unit and in fluid communication with the second cell.

2. The dialysis fluid treatment device of claim 1, wherein the third cell further comprises an ammonia sorbent.

3. The dialysis fluid treatment device of claim 1, wherein each of the first, second and third cells comprises at least two corresponding fluid pathways.

4. The dialysis fluid treatment device of claim 1, wherein the first cell and the third cell are fixedly contained within a cartridge for a wearable kidney.

5. The dialysis fluid treatment device of claim 1, wherein the second cell is removably attached to a cartridge for a wearable artificial kidney.

6. The dialysis fluid treatment device of claim 1, wherein the first cell comprises at least one of a cation exchange membrane and an anion exchange membrane.

7. The dialysis fluid treatment device of claim 1, wherein the third cell comprises at least one of a cation exchange membrane and an anion exchange membrane.

8. The dialysis fluid treatment device of claim 1 further comprising an activated carbon unit in fluid communication with the first cell.

9. The dialysis fluid treatment device of claim 1, wherein the second cell is removably attached from and in fluid communication with the first cell and the third cell.

10. A dialysis fluid treatment device comprising:

a first cell comprising an electrodialysis unit having a cathode and two opposing anodes; and

a second cell comprising a urease compartment and a sorbent compartment and in fluid communication with the first cell.

11. The dialysis fluid treatment device of claim 10, wherein the first cell further comprises an ammonia sorbent.

12. The dialysis fluid treatment device of claim 10, wherein the second cell further comprises at least one of a phosphate binder compartment and an anion exchange sorbent component.

13. The dialysis fluid treatment device of claim 10, wherein the first cell is fixedly contained within a cartridge for a wearable artificial kidney.

14. The dialysis fluid treatment device of claim 10, wherein the second cell is removably attached to a cartridge for a wearable artificial kidney.

15. The dialysis fluid treatment device of claim 10, wherein the first cell comprises at least one of a cation exchange membrane and an anion exchange membrane.

16. The dialysis fluid treatment device of claim 10, wherein the sorbent cartridge of the second cell comprises activated carbon.

17. A method for removing urea from a dialysis fluid, the method comprising:

circulating the dialysis fluid in a fluid circuit that comprises a dialysis apparatus having a cartridge comprising an electrodialysis unit and a urea removal unit;

removing urea from the dialysis fluid with the cartridge; and

recirculating the dialysis fluid back to a patient.

18. The method of claim 17, which includes allowing the urea removal unit to be detachable from the dialysis apparatus and separable from the electrodialysis unit.

19. The method of claim 17, which includes configuring the cartridge to be worn by the patient.