DETECTION OF TARGET ANALYTES USING PARTICLES AND ELECTRODES
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Accused Products
Abstract
The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined.
112 Citations
28 Claims
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1-17. -17. (canceled)
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18. A composition comprising:
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a) a substrate comprising an array of working electrodes, wherein each electrode comprises a first binding ligand; b) a plurality of colloids, each comprising; i) a second binding ligand; and ii) an electron transfer moiety; and c) a detector capable of detecting a voltage associated with electron transfer from said electron transfer moiety. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27)
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19. (canceled)
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28-37. -37. (canceled)
Specification