Thermal Block Assemblies and Instruments Providing Low Thermal Non-Uniformity for Rapid Thermal Cycling
First Claim
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1. A thermal block assembly for thermal cycling comprising:
- a sample block having a first surface and a second surface, wherein the first surface is adapted for receiving a sample support device;
a heat sink comprising a base having a first surface, a second surface and a plurality fins pendant the second surface, wherein a space between each fin provides for a flow path for air passing from an inlet side of the plurality of fins to an outlet side the plurality of fins; and
a plurality of thermal electric devices positioned between the sample block and heat sink, wherein the footprint of the plurality of thermal electric devices effectively matches the footprint of the second surface of the sample block and first surface of the heat sink to provide substantially uniform heat transfer throughout the thermal block assembly.
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Abstract
The present teachings disclose various embodiments of a thermal block assembly having low thermal non-uniformity throughout the thermal block assembly. Accordingly, various embodiments of thermal block assemblies having such low thermal non-uniformity provide for desired performance of bioanalysis instrumentation utilizing such thermal block assemblies.
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Citations
40 Claims
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1. A thermal block assembly for thermal cycling comprising:
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a sample block having a first surface and a second surface, wherein the first surface is adapted for receiving a sample support device; a heat sink comprising a base having a first surface, a second surface and a plurality fins pendant the second surface, wherein a space between each fin provides for a flow path for air passing from an inlet side of the plurality of fins to an outlet side the plurality of fins; and a plurality of thermal electric devices positioned between the sample block and heat sink, wherein the footprint of the plurality of thermal electric devices effectively matches the footprint of the second surface of the sample block and first surface of the heat sink to provide substantially uniform heat transfer throughout the thermal block assembly. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. An apparatus comprising:
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a control system; and a thermal block assembly comprising; a sample block having a first surface and a second surface, wherein the first surface is adapted for receiving a sample support device; a heat sink comprising a base having a first surface, a second surface and a plurality fins pendant the second surface, wherein a space between each fin provides for a flow path for air passing from an inlet side of the plurality of fins to an outlet side the plurality of fins; and a plurality of thermal electric devices positioned between the sample block and heat sink, wherein the footprint of the plurality of thermal electric devices effectively matches the footprint of the second surface of the sample block and first surface of the heat sink to provide substantially uniform heat transfer throughout the thermal block assembly. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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Specification