DEVICE FOR THE REMOVAL OF THROMBI FROM BLOOD VESSELS

• US 20110060359A1
• Filed: 09/20/2007
• Published: 03/10/2011
• Est. Priority Date: 09/20/2006
• Status: Abandoned Application

• Current Assignee: Phenox Gmbh
• Original Assignee: Phenox Gmbh
• Inventors: Hannes, Ralf, Monstadt, Hermann, Pracht, Holgar, Schneider, Manuel, Miloslavski, Elina
• Application Number:
  US12/441,960
• Publication Number:
  US 20110060359A1
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2010/0216 Sampling brushes
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22082 after introduction of a substance
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2017/320012 Brushes
• CPC Class Codes: A61B 2090/397 electromagnetic other than visible, e.g. microwave
• CPC Class Codes: A61L 33/126 Fibrin

Abstract

The invention relates to a device for the removal of foreign objects and thrombi from body cavities and blood vessels (12) using at least one guide wire (6, 7) provided with a distal element (2), said distal element (2) being provided with fibers (3) projecting radially outward and the device being provided with a cage (1) or tubular structure (16) which is suitable to be flatly collapsible under the external strain exerted by a micro-catheter (13) and transported inside the micro-catheter (13) and unfolds to its full cage (1) or tubular (16) structure when said external strain caused by the micro-catheter (13) is omitted, with said distal element (2) and the cage (1) or tubular (16) structure being designed so as to be longitudinally movable in relation to each other and the cage (1) or tubular structure (16) having an opening at the distal end through which the distal element (2) can be introduced into said cage (1) or tubular (16) structure. With the help of the inventive device thrombi (5) can be safely eliminated from blood vessels (12) in a simple manner.

Claims

1. Device for the removal of foreign objects and thrombi (5) from body cavities and blood vessels (12) using at least one guide wire (6, 7) provided with a distal element (2), characterized in that said distal element (2) being provided with fibers (3) projecting radially outward and the device being provided with a cage (1) or tubular structure (16) which is suitable to be flatly collapsible under the external strain exerted by a micro-catheter (13) and transported inside the micro-catheter (13) and unfolds to its full cage (1) or tubular (16) structure when said external strain caused by the micro-catheter (13) is omitted, with said distal element (2) and the cage (1) or tubular (16) structure being designed so as to be longitudinally movable in relation to each other and the cage (1) or tubular structure (16) having an opening at the distal end through which the distal element (2) can be introduced into said cage (1) or tubular (16) structure.

2. Device according to claim 1, characterized in that the fibers (3) consist of a polymer material.

3. Device according to claims 2, characterized in that the fibers (3) are made of polyurethane, polyamide, polyacrylics, polyester, polytetrafluoroethylene or polyalkylene.

4. Device according to any one of the claims 1 to 3, characterized in that the cage (1) or tubular (16) structure consists, at least partially, of a shape-memory material, in particular nitinol.

5. Device according to any one of the claims 1 to 4, characterized in that the cage (1) or tubular (16) structure on the one hand and the distal element (2) on the other are connected by means of separate guide wires (6, 7).

6. Device according any one of the claims 1 to 4, characterized in that the device is provided with only a single guide wire (6) to which distal end the distal element (2) is attached, with the cage (1) or tubular (16) structure being arranged on the guide wire so as to be movable longitudinally.

7. Device according to claim 6, characterized in that the cage (1) or tubular (16) structure is longitudinally movable on the guide wire (6) between two stop elements (14) located on the guide wire (6).

8. Device according to claim 7, characterized in that the cage (1) or tubular (16) structure, at least at one point, preferably at the proximal end of the cage (1) or tubular (16) structure narrow to such an extent that the inner diameter of the cage (1) or tubular (16) structure at this point is smaller than the outer diameter of the stop elements (14) arranged on the guide wire (6).

9. Device according to any one of the claims 1 to 8, characterized in that the cage structure (1) has been provided with a polymer skin (9) on its radial outer side.

10. Device according to claim 9, characterized in that the polymer skin (9) consist of polyurethane.

11. Device according to any one of the claims 1 to 10, characterized in that the cage structure (1) has been provided on its radial outer side with a fiber or wire braiding.

12. Device according to any one of the claims 1 to 11, characterized in that the cage structure (1) is closed at the proximal end.

13. Device according to any one of the claims 1 to 12, characterized in that the cage structure (1) has been provided with three or more, particularly four to six braces (4) extending in longitudinal direction.

14. Device according to claim 13, characterized in that the braces (4) of the cage structure (1) consist of a wire arranged so as to form loops.

15. Device according to claim 13, characterized in that the braces (4) starting out from the proximal end of the cage structure (1) extend radially outward, continue in longitudinal direction distally and, having formed into a loop, partially run back in proximal direction along the circumference of the cage structure (1).

16. Device according to any one of the claims 13 to 15, characterized in that the braces (4) are connected with each other in the distal area by means of laser spot welds and/or spiral sleeves (15).

17. Device according to any one of the claims 1 to 12, characterized in that the tubular structure (16) consists of a rolled-in metal sheet.

18. Device according to any one of the claims 1 to 17, characterized in that the cage (1) or tubular (16) structure at its proximal end terminates in a point.

19. Device according to any one of the claims 1 to 18, characterized in that the fibers (3) have a length of between 0.5 and 6 mm and preferably between 1.2 and 3.0 mm.

20. Device according to any one of the claims 1 to 19, characterized in that the fibers (3) are arranged spirally along the longitudinal axis of the distal element (2).

21. Device according to any one of the claims 1 to 20, characterized in that the radial extension of the fibers (3) of the distal element (2) increases from proximal to distal.

22. Device according to any one of the claims 1 to 21, characterized in that the fibers (3) in the proximal area of the distal element (2) are harder than in the distal area of the distal element (2).

23. Device according to any one of the claims 1 to 22, characterized in that the fibers (3) form an angle with longitudinal axis of the device that ranges between 70°

and 110°

, preferably between 80° and

90°

.

24. Device according to any one of the claims 1 to 23, characterized in that the fibers (3) are secured or attached to the distal element (2) by braiding, clamping, bonding, knotting, welding and/or fusing.

25. Device according to any one of the claims 1 to 24, characterized in that the ends of the fibers (3) located radially outward are provided with slabs or nubs.

26. Device according to any one of the claims 1 to 25, characterized in that the ends of the fibers (3) located radially outward are at least in part connected with each other by means of loops.

27. Device according to any one of the claims 1 to 26, characterized in that the fibers (3), at least partially, protrude differently far radially outward at the sides of the distal element (2).

28. Device according to any one of the claims 1 to 27, characterized in that the cage (1) or tubular (16) structure and/or the fibers (3) are provided with a coating.

29. Device according to claim 28, characterized in that the coating has a thrombolytic effect.

30. Device according to any one of the claims 1 to 29, characterized in that the distal element (2) is designed so as to be slightly longer than the cage (1) or tubular (16) structure.

31. Device according to any one of the claims 1 to 30, characterized by one or several radiopaque markers.

32. Device according to any one of the claims 1 to 31 in combination with a guide catheter and/or micro-catheter (13).

33. Device according to claim 32, characterized in that the guide or micro-catheter (13) is designed as aspiration catheter.

34. Device for the removal of foreign objects and thrombi (5) from body cavities and blood vessels (12) using at least one guide wire (6, 7) provided with a distal element (2), in particular according to any one of the claims 1 to 33, characterized in that the distal element (2) is provided with a fibrin-specific thrombolytic agent.

35. Device according to claim 34, characterized in that the distal element is provided with fibers (3) projecting radially outward.

36. Device according to claim 34, characterized in that the distal element (2) has a cage structure.

37. Device according to any one of the claims 34 to 36, characterized in that the fibrinolytic agent acts irrespectively of the formation of plasmin.