CARDIAC NEUROMODULATION AND METHODS OF USING SAME
First Claim
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1. A method of treating sequelae of myocardial ischemia in a patient comprising:
- identifying a patient suffering from or that is susceptible to myocardial ischemia;
implanting a stimulation device into the patient to electrically stimulate the spinal cord, wherein the stimulation device comprises a plurality of electrodes and a generator in which at least one electrode is placed near the spinal cord;
activating the stimulation device to deliver electrical stimulation to the spinal cord to suppress intrinsic cardiac nerve activity thereby treating sequelae of myocardial ischemia.
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Abstract
The present invention relates in general to methodologies for the treatment quenching preconditioning and communication between the intrinsic cardiac nervous system and an electrical stimulus. In particular, the present invention utilizes spinal cord stimulation to alter and/or affect the intrinsic cardiac nervous system and thereby protect the myocytes, stabilize myocardial electrical instability and/or alleviate or diminish cardiac pathologies.
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Citations
29 Claims
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1. A method of treating sequelae of myocardial ischemia in a patient comprising:
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identifying a patient suffering from or that is susceptible to myocardial ischemia; implanting a stimulation device into the patient to electrically stimulate the spinal cord, wherein the stimulation device comprises a plurality of electrodes and a generator in which at least one electrode is placed near the spinal cord; activating the stimulation device to deliver electrical stimulation to the spinal cord to suppress intrinsic cardiac nerve activity thereby treating sequelae of myocardial ischemia. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method of stabilizing mechanical activity of the heart comprising:
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identifying a subject susceptible to or suffering from a cardiac pathology; implanting a stimulation device into the identified patient to electrically stimulate the spinal cord, wherein the stimulation device comprises a plurality of electrodes and a generator in which at least one electrode is placed near the spinal cord; activating the stimulation device to deliver electrical stimulation to the spinal cord to suppress intrinsic cardiac nerve activity thereby stabilizing mechanical activity of the heart. - View Dependent Claims (18, 19, 20, 21)
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22. A method of treating heart failure in a patient comprising:
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providing a stimulation device capable of generating an electrical signal, wherein the stimulation device comprises a plurality of electrodes and a generator in which at least one electrode is placed near the spinal cord; and activating the stimulation device to deliver the electrical signal to the spinal cord to suppress intrinsic cardiac nerve activity. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29)
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Specification