APPLICATOR FOR ENDOSCOPIC TREATMENT OF BILIARY DISEASE

• US 20110071350A1
• Filed: 11/22/2010
• Published: 03/24/2011
• Est. Priority Date: 11/30/2007
• Status: Active Grant

• Current Assignee: Treus Medical, Inc.
• Original Assignee: Treus Medical, Inc.
• Inventors: Van Dam, Jacques, Milroy, J. Craig, Ohline, R. Matthew
• Granted Patent: US 9,282,968 B2
• Time in Patent Office: Days
• US Class Current: 600/106
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 17/1114 of the digestive tract, e.g. bowels or oesophagus
• CPC Class Codes: A61B 2017/00278 Transorgan operations, e.g. transgastric
• CPC Class Codes: A61B 2017/1139 Side-to-side connections, e.g. shunt or X-connections
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/064 with special features to facilitate anastomotic coupling anastomosis of natural blood vessels A61B17/11
• CPC Class Codes: A61F 2/24 Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
• CPC Class Codes: A61F 2/2493 Transmyocardial revascularisation [TMR] devices
• CPC Class Codes: A61F 2002/041 Bile ducts
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61M 2025/0233 specifically adapted for attaching to a body wall by means which are on both sides of the wall, e.g. for attaching to an abdominal wall
• CPC Class Codes: A61M 2025/1072 having balloons with two or more compartments
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence
• CPC Class Codes: A61M 27/008 pre-shaped, for use in the urethral or ureteral tract
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104

Abstract

The application discloses devices, systems, kits and methods for treating biliary disease. Device comprise, for example, a component configured for deployment to a lumen of a gallbladder or gallbladder duct which has a proximal end and a distal end with a lumen extending therethrough and a fluid or gas delivery apparatus at its distal end.

Claims

1. An applicator adapted for endoscopic delivery to treat biliary disease comprising:

an elongated member having a proximal end and a distal end adapted to be delivered transluminally from an exterior surface of a gallbladder to an interior lumen of the gallbladder without use of a common bile duct, the elongated member having a length adapted for delivery through a mammalian esophagus, stomach and duodenum, an outer diameter smaller than a mammalian esophagus;

a channel positioned within the elongated member with an aperture at the distal tip of the elongated member wherein the channel extends a length of the elongated member and is sized to deliver at least one of a guiding element or stirring element through the distal channel aperture; and

one or more material delivery apertures positioned at a distal end of the elongated member adaptable to deliver a material to the lumen within the gallbladder or a gallbladder duct, wherein the material delivery apertures have a smaller diameter than the channel aperture.

2. The applicator of claim 1 wherein the distal end has an angular orientation relative to a length of the elongated member.

3. The applicator of claim 1 wherein the distal end is adapted to deliver a material with at least one of a 360 degree radial pattern, a sharp stream, and a cone shape.

4. The applicator of claim 1 wherein the distal end has an articulating member.

5. The applicator of claim 1 further is adapted to apply a vacuum.

6. The applicator of claim 1 wherein the distal end is adapted to apply an adhesive to a lumen of the gallbladder.

7. The applicator of claim 1 wherein the applicator is configured for deployment by an endoscope.

8. The applicator of claim 1 wherein the applicator is configured for deployment using at least one of a needle, guidewire, or guidance catheter.

9. The applicator of claim 1 wherein the lumen is configurable to provide restrictable fluid flow.

10. The applicator of claim 9 further comprising one or more fluid control components.

11. The applicator of claim 1 further comprising a valve.

12. The applicator of claim 11 wherein the valve is at least one of a flow-restrictor or one-way valve.

13. The applicator of claim 1 wherein the tool is flexible.

14. The applicator of claim 1 wherein the tool is an elongate tube adapted and configured to extend into the gastrointestinal tract.

15. A method of treating biliary disease comprising:

a. accessing a lumen associated with a gallbladder or a gallbladder duct;

b. defunctionalizing at least one of the gallbladder duct or the gallbladder; and

c. leaving the gallbladder in situ.

16. A kit for treating biliary disease comprising:

(a) a device adaptable to deliver to a lumen of a gallbladder or gallbladder duct; and

optionally (b) a compound for delivery to a tissue.