METHODS AND COMPOSITIONS FOR PRESERVING PLATELETS
First Claim
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1. A method for preserving platelets, comprising:
- mixing platelets with a platelet preservation composition to form a platelet preparation, said platelet preservation composition comprises an effective amount of an antiplatelet agent and an effective amount of an anticoagulant;
storing the platelet preparation for a desired period of time; and
removing the antiplatelet agent and the anticoagulant from the platelet preparation by diafiltration prior to transfusion of the platelets.
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Abstract
The present invention relates to methods for preserving platelet. In one embodiment, the method includes the steps of mixing platelets with a platelet preservation composition to form a platelet preparation, storing the platelet preparation for a desired period of time, and removing the antiplatelet agent and the anticoagulant from the platelet preparation by diafiltration prior to transfusion of the platelets. The platelet preservation composition comprises an effective amount of an antiplatelet agent and an effective amount of an anticoagulant.
11 Citations
20 Claims
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1. A method for preserving platelets, comprising:
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mixing platelets with a platelet preservation composition to form a platelet preparation, said platelet preservation composition comprises an effective amount of an antiplatelet agent and an effective amount of an anticoagulant; storing the platelet preparation for a desired period of time; and removing the antiplatelet agent and the anticoagulant from the platelet preparation by diafiltration prior to transfusion of the platelets. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method for preserving platelets, comprising:
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mixing platelets with a platelet preservation composition to form a platelet preparation, said platelet preservation composition comprises an effective amount of an antiplatelet agent and an effective amount of an anticoagulant; storing the platelet preparation for a desired period of time; and passing the platelet preparation through a porous material that specifically binds to the antiplatelet agent and anticoagulant to remove the antiplatelet agent and the anticoagulant from the platelet preparation prior to transfusion of the platelets. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
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Specification