HEART SOUND TRACKING SYSTEM AND METHOD

• US 20110077543A1
• Filed: 12/10/2010
• Published: 03/31/2011
• Est. Priority Date: 04/17/2007
• Status: Active Grant

• Current Assignee: Abhilash Patangay, Gerrard M. Carlson, Krzysztof Z. Siejko
• Original Assignee: Abhilash Patangay, Gerrard M. Carlson, Krzysztof Z. Siejko
• Inventors: Patangay, Abhilash, Carlson, Gerrard M., Siejko, Krzysztof Z.
• Granted Patent: US 8,332,034 B2
• Time in Patent Office: Days
• US Class Current: 600/528
• CPC Class Codes: A61B 7/00 Instruments for auscultation
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

A system and method provide heart sound tracking, including an input circuit, configured to receive heart sound information, and a heart sound recognition circuit. The heart sound recognition circuit can be coupled to the input circuit and can be configured to recognize, within a particular heart sound of a particular heart sound waveform, a first intra heart sound energy indication and a corresponding first intra heart sound time indication using the heart sound information from the particular heart sound waveform and the heart sound information from at least one other heart sound waveform. The particular heart sound can include at least a portion of one of S1, S2, S3, and S4. Further, the first intra heart sound energy indication and the corresponding first intra heart sound time indication can correspond to the at least a portion of one of S1, S2, S3, and S4, respectively.

Claims

1. A system, comprising:

an input circuit, configured to receive heart sound information;

a heart sound recognition circuit, coupled to the input circuit, configured to recognize, within a particular heart sound of a particular heart sound waveform, a first intra heart sound energy indication and a corresponding first intra heart sound time indication using the heart sound information from the particular heart sound waveform and the heart sound information from at least one other heart sound waveform;

wherein the particular heart sound includes at least a portion of one of S1, S2, S3, and S4; and

wherein the first intra heart sound energy indication and the corresponding first intra heart sound time indication corresponds to the at least a portion of one of S1, S2, S3, and S4, respectively.

2. The system of claim 1, wherein the input circuit is configured to receive S2 information;

and

wherein the heart sound recognition circuit is configured to recognize, within the S2 of the particular heart sound waveform, an intra S2 energy indication and a corresponding intra S2 time indication using the S2 information from the particular heart sound waveform and the S2 information from at least one other heart sound waveform.

3. The system of claim 1, wherein the heart sound waveform includes at least a portion of at least one physiological cycle.

4. The system of claim 3, wherein the physiological cycle includes a cardiac cycle.

5. The system of claim 3, wherein the particular heart sound of a particular heart sound waveform includes an ensemble averaged heart sound over multiple physiological cycles.

6. The system of claim 1, wherein the at least one other heart sound waveform includes an immediately preceding heart sound waveform to the particular heart sound waveform.

7. The system of claim 1, wherein the heart sound recognition circuit is configured to recognize the first intra heart sound energy indication and the corresponding first intra heart sound time indication using a heart sound template.

8. The system of claim 7, wherein the heart sound template includes at least a portion of the heart sound information from the at least one other heart sound waveform.

9. The system of claim 8, wherein the heart sound recognition circuit is configured to recognize the first intra heart sound energy indication and the corresponding first intra heart sound time indication using a cross correlation between at least a portion of the heart sound information from the particular heart sound waveform and at least a portion of the heart sound template.

10. The system of claim 1, including:

an implantable medical device, the implantable medical device including;

a heart sound sensor, configured to sense a heart sound signal; and

a heart sound feature detector, coupled to the heart sound sensor, the heart sound feature detector configured to detect at least one heart sound feature using the heart sound signal; and

wherein the heart sound information includes the at least one heart sound feature.

11. The system of claim 1, wherein the heart sound recognition circuit includes a detection circuit, the detection circuit configured to:

detect at least one first candidate heart sound for the particular heart sound of the at least one other heart sound waveform using the heart sound information, wherein the at least one first candidate heart sound includes an intra heart sound energy indication and a corresponding intra heart sound time indication; and

detect at least one second candidate heart sound for the particular heart sound of the particular heart sound waveform using the heart sound information, wherein the at least one second candidate heart sound includes an intra heart sound energy indication and a corresponding intra heart sound time indication; and

wherein the heart sound recognition circuit is configured to recognize the first intra heart sound energy indication and the corresponding first intra heart sound time indication using;

the at least one detected first candidate heart sound; and

the at least one detected second candidate heart sound.

12. The system of claim 11, wherein the at least one other heart sound waveform includes an immediately preceding heart sound waveform to the particular heart sound waveform.

13. The system of claim 11, wherein the heart sound recognition circuit includes a cost analysis circuit, coupled to the detection circuit, the cost analysis circuit configured to calculate a cost for the at least one second candidate heart sound, the calculated cost including:

a jump penalty indicative of a temporal cost associated with the at least one second candidate heart sound; and

a local score indicative of a local benefit associated with the at least one second candidate heart sound; and

wherein the heart sound recognition circuit is configured to recognize the first intra heart sound energy indication and the corresponding first intra heart sound time indication using the calculated cost.

14. The system of claim 13, wherein the heart sound recognition circuit is configured to calculate a back pointer that indicates a pointer from the at least one second candidate heart sound to an optimal at least one first candidate heart sound using the cost analysis.

15. The system of claim 1, wherein the heart sound recognition circuit includes a coasting circuit, coupled to the heart sound recognition circuit, configured to disregard the recognized first intra heart sound energy indication and the corresponding recognized first intra heart sound time indication using a comparison of:

the recognized first intra heart sound energy indication and the corresponding recognized first intra heart sound time indication; and

at least one other recognized intra heart sound energy indication and a corresponding at least one other recognized intra heart sound time indication within the particular heart sound of at least one other heart sound waveform.

16. The system of claim 15, wherein the heart sound recognition circuit includes a recapture circuit, coupled to the coasting circuit, configured recapture the disregarded recognized first intra heart sound energy indication and the corresponding disregarded recognized first intra heart sound time indication using a comparison of:

the disregarded recognized first intra heart sound energy indication and the corresponding disregarded recognized first intra heart sound time indication; and

at least one other recognized intra heart sound energy indication and a corresponding at least one other recognized intra heart sound time indication within the particular heart sound of at least one other heart sound waveform.

17. A method, comprising:

receiving heart sound information;

recognizing a first intra heart sound energy indication and a corresponding first intra heart sound time indication within a particular heart sound of a particular heart sound waveform using the heart sound information from the particular heart sound waveform and the heart sound information from at least one other heart sound waveform;

wherein the recognizing the first intra heart sound energy indication and the corresponding first intra heart sound time indication within the particular heart sound includes recognizing within at least a portion of one of S1, S2, S3, and S4; and

wherein the recognizing the first intra heart sound energy indication and the corresponding first intra heart sound time indication corresponds to the at least a portion of one of S1, S2, S3, and S4, respectively.

18. The method of claim 17, wherein the receiving the heart sound information includes receiving S2 information;

wherein the recognizing the first intra heart sound energy indication and the corresponding first intra heart sound time indication within the particular heart sound of the particular heart sound waveform includes recognizing an intra S2 energy indication and a corresponding intra S2 time indication within an S2 of the particular heart sound waveform; and

wherein the using the heart sound information from the particular heart sound waveform and the heart sound information from the at least one other heart sound waveform includes using the S2 information from the particular heart sound waveform and the S2 information from at least one other heart sound waveform.

19. The method of claim 17, wherein the heart sound waveform includes at least a portion of at least one physiological cycle.

20. The method of claim 19, wherein the physiological cycle includes a cardiac cycle.

21. The method of claim 19, wherein the particular heart sound of the particular heart sound waveform includes an ensemble averaged heart sound over multiple physiological cycles.

22. The method of claim 17, wherein the using the heart sound information from the at least one other heart sound waveform includes using the heart sound information from an immediately preceding heart sound waveform to the particular heart sound waveform.

23. The method of claim 17, wherein the recognizing the first intra heart sound energy indication and the corresponding first intra heart sound time indication includes using a heart sound template and comparing the heart sound information from the particular heart sound waveform to the heart sound template.

24. The method of claim 23, wherein the using the heart sound template includes updating the heart sound template using at least a portion of the heart sound information from the at least one other heart sound waveform.

25. The method of claim 23, wherein the recognizing the first intra heart sound energy indication and the corresponding first intra heart sound time indication includes cross correlating between at least a portion of the heart sound information from the particular heart sound waveform and at least a portion of the heart sound template.

26. The method of claim 17, including:

implantably sensing a heart sound signal;

implantably detecting at least one heart sound feature using the heart sound signal; and

wherein the using the heart sound information includes using the at least one heart sound feature.

27. The method of claim 17, including:

detecting at least one first candidate heart sound for the particular heart sound of the at least one other heart sound waveform using the heart sound information, wherein detecting the at least one first candidate heart sound includes detecting an intra heart sound energy indication and a corresponding intra heart sound time indication;

detecting at least one second candidate heart sound for the particular heart sound of the particular heart sound waveform using the heart sound information, wherein detecting the at least one second candidate heart sound includes detecting an intra heart sound energy indication and a corresponding intra heart sound time indication; and

wherein the recognizing the first intra heart sound energy indication and the corresponding first intra heart sound time indication includes using;

the at least one detected first candidate heart sound; and

the at least one detected second candidate heart sound.

28. The method of claim 27, wherein the recognizing the at least one first candidate heart sound for the particular heart sound of the at least one other heart sound waveform includes recognizing the at least one first candidate heart sound for the particular heart sound of an immediately preceding heart sound waveform to the particular heart sound waveform.

29. The method of claim 27, including calculating a cost for the at least one second candidate heart sound, including:

calculating a jump penalty indicative of a temporal cost associated with the at least one second candidate heart sound; and

calculating a local score indicative of a local benefit associated with the at least one second candidate heart sound; and

wherein the recognizing the first intra heart sound energy indication and the corresponding first intra heart sound time indication includes using the calculated cost.

30. The method of claim 29, including calculating a back pointer that indicates a pointer from the at least one second candidate heart sound to an optimal at least one first candidate heart sound using the cost analysis.

31. The method of claim 17, including:

disregarding the recognized first intra heart sound energy indication and the corresponding recognized first intra heart sound time indication using a comparison of;

the recognized first intra heart sound energy indication and the corresponding recognized first intra heart sound time indication; and

at least one other recognized intra heart sound energy indication and a corresponding at least one other recognized intra heart sound time indication within the particular heart sound of at least one other heart sound waveform.

32. The method of claim 31, including:

recapturing the disregarded recognized first intra heart sound energy indication and the corresponding disregarded recognized first intra heart sound time indication using a comparison of;

the disregarded recognized first intra heart sound energy indication and the corresponding disregarded recognized first intra heart sound time indication; and

at least one other recognized intra heart sound energy indication and a corresponding at least one other recognized intra heart sound time indication within the particular heart sound of at least one other heart sound waveform.

33. A non-transitory machine-readable medium containing instructions that, when executed by one or more processors, causes the one or more processors to:

receive heart sound information;

recognize a first intra heart sound energy indication and a corresponding first intra heart sound time indication within a particular heart sound of a particular heart sound waveform using the heart sound information from the particular heart sound waveform and the heart sound information from at least one other heart sound waveform;

wherein the first intra heart sound energy indication and the corresponding first intra heart sound time indication within the particular heart sound includes at least a portion of one of S1, S2, S3, and S4; and

wherein the first intra heart sound energy indication and the corresponding first intra heart sound time indication correspond to the at least a portion of one of S1, S2, S3, and S4, respectively.

34. The non-transitory machine-readable medium of claim 33, wherein the machine readable medium contains instructions that, when executed by the one or more processors, causes the one or more processors to:

detect at least one first candidate heart sound for the particular heart sound of the at least one other heart sound waveform using the heart sound information, wherein detecting the at least one first candidate heart sound includes detecting an intra heart sound energy indication and a corresponding intra heart sound time indication;

detect at least one second candidate heart sound for the particular heart sound of the particular heart sound waveform using the heart sound information, wherein detecting the at least one second candidate heart sound includes detecting an intra heart sound energy indication and a corresponding intra heart sound time indication;

recognize the first intra heart sound energy indication and the corresponding first intra heart sound time indication using;

the at least one detected first candidate heart sound; and

the at least one detected second candidate heart sound; and

wherein the particular heart sound of the particular heart sound waveform includes an ensemble averaged heart sound over multiple physiological cycles.

35. The non-transitory machine-readable medium of claim 34, wherein the machine readable medium contains instructions that, when executed by the one or more processors, causes the one or more processors to:

calculate a jump penalty indicative of a temporal cost associated with the at least one second candidate heart sound; and

calculate a local score indicative of a local benefit associated with the at least one second candidate heart sound; and

calculate a cost for the at least one second candidate heart sound using the jump penalty and the local score;

recognize the first intra heart sound energy indication and the corresponding first intra heart sound time indication includes using the calculated cost.

36. The non-transitory machine-readable medium of claim 33, wherein the machine readable medium contains instructions that, when executed by the one or more processors, causes the one or more processors to:

disregard the recognized first intra heart sound energy indication and the corresponding recognized first intra heart sound time indication using a comparison of;

the recognized first intra heart sound energy indication and the corresponding recognized first intra heart sound time indication; and

at least one other recognized intra heart sound energy indication and a corresponding at least one other recognized intra heart sound time indication within the particular heart sound of at least one other heart sound waveform.