BI-DIRECTIONAL MOTION OF A LORENTZ-FORCE ACTUATED NEEDLE-FREE INJECTOR (NFI)

• US 20110082388A1
• Filed: 09/10/2010
• Published: 04/07/2011
• Est. Priority Date: 07/09/2008
• Status: Active Grant

• Current Assignee: Massachusetts Institute of Technology
• Original Assignee: Massachusetts Institute of Technology
• Inventors: Taberner, Andrew J., Hunter, Ian W., Hogan, N. Catherine
• Granted Patent: US 8,398,583 B2
• Time in Patent Office: Days
• US Class Current: 600/573
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 2010/008 Interstitial fluid
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2205/8287 operated by an external magnetic or electromagnetic field
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Abstract

The present invention relate to a method and corresponding apparatus for extraction of a sample from a sample source. A fluid is injected into the sample source and the sample source is vibrated. A sample is withdrawn from the vibrated sample source and the sample source is evaluated by measuring one or more identifying parameters in the withdrawn sample.

Claims

1. A method for extraction of a sample from a sample source, the method comprising:

injecting a fluid into the sample source;

vibrating the sample source and withdrawing a sample from the sample source; and

evaluating the sample source as a function of measuring one or more identifying parameters in the withdrawn sample.

2. The method of claim 1 wherein the sample source includes tissue of a biological body.

3. The method of claim 1 wherein the injected fluid is physiological saline.

4. The method of claim 1 wherein the withdrawn sample is an extracellular fluid.

5. The method of claim 1 wherein the one or more identifying parameters include metabolic or proteomic parameters.

6. An apparatus for extraction of a sample from a sample source, the apparatus comprising:

a bi-directional needle-free injector that injects a fluid into the sample source, vibrates the sample source to facilitate withdrawal of the sample from the sample source and withdraws a sample from the sample source; and

a sample evaluator that evaluates the sample source as a function of measuring one or more identifying parameters in the withdrawn sample.

7. The apparatus of claim 6 wherein the sample source includes tissue of a biological body.

8. The apparatus of claim 6 wherein the injected fluid is physiological saline.

9. The apparatus of claim 6 wherein the withdrawn sample is an extracellular fluid.

10. The apparatus of claim 6 wherein the one or more identifying parameters include metabolic or proteomic parameters.

11-29. -29. (canceled)