Combination Therapies for the Treatment of Obesity
First Claim
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1. A pharmaceutical composition comprising topiramate, phentermine, and metformin, or pharmaceutically acceptable salts or solvates of any of them;
- and at least one pharmaceutically acceptable carrier or excipient.
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Abstract
Described are pharmaceutical compositions comprising topiramate, phentermine, and metformin, and at least one pharmaceutically acceptable carrier or excipient. Another aspect of the present invention relates to a method of treating a patient suffering from obesity or needing to lose weight, comprising the step of co-administering to said patient a therapeutically effective amount of topiramate, phentermine, and metformin. In certain embodiments, an aforementioned method is practiced in conjunction or tandem with a medical procedure or the use of a medical device or both.
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32 Claims
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1. A pharmaceutical composition comprising topiramate, phentermine, and metformin, or pharmaceutically acceptable salts or solvates of any of them;
- and at least one pharmaceutically acceptable carrier or excipient.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
- 11. A method of treating obesity or achieving weight loss, comprising the step of co-administering to a subject in need thereof a therapeutically effective amount of topiramate, phentermine, and metformin, or pharmaceutically acceptable salts or solvates of any of them.
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32. A method of treating a malady, comprising the step of co-administering to a subject in need thereof a therapeutically effective amount of topiramate, phentermine, and metformin, or pharmaceutically acceptable salts or solvates of any of them, wherein the malady is selected from the group consisting of type 2 diabetes, shortness of breath, gallbladder disease, hypertension, elevated blood cholesterol levels, endometrial cancer, breast cancer, prostate cancer, colon cancer, osteoarthritis, other orthopedic problems, reflux esophagitis, snoring, menstrual irregularities, infertility, heart trouble, dyslipidemia, coronary heart disease, stroke, hyperinsulinemia, depression, anxiety, gout, fatty liver disease, insulin resistance, pre-diabetes, beta-cell dysfunction, sleep apnea, obstructive sleep apnea, hypopnea, and visceral adiposity.
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