ADMINISTRATION DEVICE HAVING PATIENT STATE MONITOR

• US 20110082445A1
• Filed: 10/08/2010
• Published: 04/07/2011
• Est. Priority Date: 04/11/2008
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Friedli, Kurt, Van der Helm, Wim, Remde, Axel
• Granted Patent: US 9,078,965 B2
• Time in Patent Office: Days
• US Class Current: 604/890.1
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3327 Measuring
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2230/63 Motion, e.g. physical activity
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

Embodiments disclosed herein include systems and methods for administering a drug over a time period. One embodiment of a system includes an administration unit, a housing that houses the administration unit, and a controller unit adapted to receive an alarm triggering signal. Also included in some embodiments is an alarming unit that is adapted to generate an alarm signal on reception of the alarm triggering signal. Some embodiments include a patient state monitor that includes a motion-sensitive sensor unit that is reactive on patient motion. The patient state monitor may be adapted to process a sensor signal generated by the motion-sensitive sensor unit. The patient state monitor may also be adapted to transmit an alarm triggering signal to the controller unit if a patient motion level is below a predefined motion level, as determined by the length of time without patient motion.

Claims

1. An administration device for administration of a liquid drug over an extended time period to a patient, comprising:

an administration unit;

a housing that houses the administration unit, the housing being adapted to be carried by a patient over an extend time period;

a controller unit adapted to control operation of the administration unit, the controller unit further adapted to receive an alarm triggering signal;

an alarming unit that is coupled to the controller unit, the alarming unit adapted to generate an alarm signal on reception of the alarm triggering signal by the controller unit; and

a patient state monitor that includes a motion-sensitive sensor unit, the motion-sensitive sensor unit being reactive on patient motion, the patient state monitor being adapted to process a sensor signal (SS) generated by the motion-sensitive sensor unit, the patient state monitor being further adapted to generate the alarm triggering signal and to transmit the alarm triggering signal to the controller unit if processing of the sensor signal (SS) indicates a patient motion level is below a predefined motion level, the predefined motion level being defined by length of time-periods without patient motion that can be expected for a conscious human.

2. The administration device of claim 1, wherein motion-sensitive sensor unit is coupled to a motion sensor unit housing, the motion sensor unit housing being separate from the housing.

3. The administration device of claim 1, wherein the motion-sensitive sensor unit includes at least one of the following:

a tilt sensor, a vibration sensor, a shock sensor, and an acceleration sensor.

4. The administration device of claim 1, wherein the motion-sensitive sensor unit includes at least one binary switching sensor.

5. The administration device of claim 1, wherein the patient state monitor includes an energy storage, the motion-sensitive sensor unit being adapted to modify an energy (E) stored by the energy storage.

6. The administration device of claim 1, wherein the controller unit is adapted to control the administration unit to stop drug administration on reception of the alarm triggering signal.

7. The administration device of claim 1, wherein the patient state monitor includes a counter unit, the counter unit being adapted to count a number (N) of consecutive monitoring intervals without substantive patient motion.

8. The administration device of claim 7, wherein the patient state monitor is adapted to generate the alarm triggering signal if a counter state (N) equals a threshold number (TN).

9. A method for detecting a patient motion level below a predefined motion level, comprising the steps of:

providing an administration device that is adapted to be carried by a patient, the administration device being further adapted for drug administration over an extended period of time, the administration device including a motion-sensitive sensor unit, the motion-sensitive sensor unit being reactive on patient motion; and

processing a sensor signal (SS) generated by the motion-sensitive sensor unit and generating an alarm triggering signal if processing of the sensor signal (SS) indicates the patient motion level below the predefined motion level, the predefined motion level being defined by the length of time-periods without patient motion that can be expected for a conscious human.

10. The method of claim 9, further comprising the step of modifying the predefined motion level.

11. The method of claim 9, further comprising the step of modifying the predefined motion level based on at least one of the following:

time of day, day of week, and past patient motion.

12. The method of claim 9, further comprising the step of modifying the energy (E) stored in an energy storage, wherein modifying an energy (E) is triggered by patient motion.

13. The method of claim 9, further comprising the step of sampling a patient state signal (PS), the patient state signal (PS) being derived from the sensor signal (SS) at defined sampling points in times, the sampling points in time defining monitoring intervals.

14. The method of claim 9, further comprising the step of sampling a patient state signal (PS), the patient state signal (PS) being derived from the sensor signal (SS) during sampling intervals, the sampling intervals alternating with non-sampling intervals.

15. The method of claim 9, further comprising the step of providing monitoring intervals and counting a number (N) of consecutive monitoring intervals without substantive patient motion.