CENTRIFUGAL FORCE BASED MICROFLUIDIC SYSTEM AND BIO CARTRIDGE FOR THE MICROFLUIDIC SYSTEM

• US 20110085950A1
• Filed: 10/08/2009
• Published: 04/14/2011
• Est. Priority Date: 10/08/2009
• Status: Abandoned Application

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: KIM, Ki Eun, LEE, Jung Nam, LEE, Jeong Gun, LEE, Beom Seok, CHO, Yoon Kyoung
• Application Number:
  US12/575,635
• Publication Number:
  US 20110085950A1
• Time in Patent Office: Days
• US Class Current: 422/504
• CPC Class Codes: B01L 2200/027 for microfluidic devices
• CPC Class Codes: B01L 2200/04 Exchange or ejection of cartridges, containers or reservoirs
• CPC Class Codes: B01L 2200/12 Specific details about manufacturing devices
• CPC Class Codes: B01L 2300/0806 Standardised forms, e.g. compact disc [CD] format
• CPC Class Codes: B01L 2300/087 Multiple sequential chambers
• CPC Class Codes: B01L 2400/0409 centrifugal forces
• CPC Class Codes: B01L 2400/0677 phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
• CPC Class Codes: B01L 3/50273 characterised by the means or forces applied to move the fluids micropumps F04B19/006, of the membrane type F04B43/043
• CPC Class Codes: G01N 2035/00495 Centrifuges
• CPC Class Codes: G01N 21/07 Centrifugal type cuvettes G01N21/09 takes precedence
• CPC Class Codes: G01N 35/00029 provided with flat sample substrates, e.g. slides G01N35/028 takes precedence

Abstract

A microfluidic system based on centrifugal force and a bio cartridge for the microfluidic system are provided. The system includes a spindle motor, a rotatable frame detachably mounted on the motor and having a plurality of cells separated by partition walls, and the bio cartridge detachably accommodated in one of the plurality of cells. The bio cartridge includes a chamber for storing a fluid, a channel for transporting the fluid, and a valve for controlling the flow of the fluid. The valve may include a phase transition material, and exothermic minute particles dispersed in the material and generating heat when energy is applied thereto.

Claims

1. A microfluidic system comprising:

a spindle motor;

a frame detachably connected to the spindle motor and comprising a plurality of cells separated by partition walls; and

at least one cartridge detachably accommodated in at least one of the plurality of cells,

wherein the cartridge comprises a chamber configured to store a fluid, a channel configured to transport the fluid, and a valve configured to control a flow of the fluid within the channel.

2. The microfluidic system according to claim 1, wherein the valve comprises a phase transition material, and a plurality of minute particles which are dispersed in the phase transition material and generate heat when energy is applied thereto.

3. The microfluidic system according to claim 2, wherein the minute particles are metal oxides.

4. The microfluidic system according to claim 2, wherein the phase transition material is wax, gel, or thermoplastic resin.

5. The microfluidic system according to claim 2, further comprising an external energy source which applies energy to the valve so that the minute particles absorb the energy and thereby generate heat which causes the phase transition material to undergo a phase transition to be able to flow.

6. The microfluidic system according to claim 5, wherein the energy source is configured to emit electromagnetic waves to the valve.

7. The microfluidic system according to claim 1, further comprising a dummy cartridge detachably accommodated in at least one of the cells which is not loaded with the cartridge, so as to control a rotational balance of the frame.

8. The microfluidic system according to claim 1, wherein the cell has a fanwise shape extending from a rotational center of the frame, and the cartridge has a fanwise shape corresponding to the shape of the cell.

9. The microfluidic system according to claim 1, further comprising a fixing portion which detachably secures the cartridge in the cell, the fixing portion comprising at least one hook member disposed inside of the cell.

10. The microfluidic system according to claim 1, wherein further comprising a cover member which is detachably coupled to the frame to close the cell thereby securing the cartridge in the cell.

11. The microfluidic system according to claim 1, further comprising a test kit detachably mounted in the cartridge and including a test strip for indicating an existence of a particular substance.

12. A bio cartridge detachably accommodated in a cell of a frame of a microfluidic device, the bio cartridge comprising:

a chamber configured to store a fluid;

a channel configured to transport the fluid; and

a valve configured to control a flow of the fluid within the channel.

13. The bio cartridge according to claim 12, wherein the valve comprises a phase transition material, and a plurality of minute particles which are dispersed in the phase transition material and generate heat when energy is applied thereto.

14. The bio cartridge according to claim 13, wherein the minute particles are minute metal oxides.

15. The bio cartridge according to claim 13, wherein the phase transition material is wax, gel, or thermoplastic resin.

16. The bio cartridge according to claim 13, wherein the bio cartridge has a fanwise shape corresponding to a shape of the cell of the frame.

17. The bio cartridge according to claim 13, further comprising a test kit detachably mounted in the bio cartridge and including a test strip for indicating an existence of a particular substance.

18. A microfluidic device comprising:

a frame having a disk shape, the frame comprising at least one cell; and

at least one cartridge detachably accommodated in the at least one cell, the cartridge comprising a test unit configured to perform a test on a sample fluid based on centrifugal force.

19. The microfluidic device according to claim 18, wherein the test unit comprises a chamber configured to store a fluid, a channel configured to transport the fluid, and a valve configured to control a flow of the fluid within the channel.

20. The microfluidic device according to claim 19, wherein the valve comprises a phase transition material, and a plurality of minute particles which are dispersed in the phase transition material and generate heat when energy is applied thereto.

21. The microfluidic device according to claim 18, wherein the frame comprises a plurality of cells separated by partition walls.

22. The microfluidic device according to claim 18, further comprising a fixing portion which detachably secures the cartridge in the cell, the fixing portion comprising at least one hook member disposed inside of the cell.

23. The microfluidic device according to claim 18, further comprising a cover member which is detachably coupled to the frame to close the cell thereby securing the cartridge in the cell.