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COMPOSITION AND METHOD FOR THE REPAIR AND REGENERATION OF CARTILAGE AND OTHER TISSUES

  • US 20110086008A1
  • Filed: 10/08/2010
  • Published: 04/14/2011
  • Est. Priority Date: 06/29/2000
  • Status: Active Grant
First Claim
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1. A self-gelling and injectable polymer composition for repairing or regenerating a tissue of a patient comprising a polymer solution admixed with blood or a component thereof,wherein the polymer solution includes at least one selected from the group consisting of a polysaccharide, a protein, a polyamino acid, a polylactic acid, a polydycolic acid, a synthetic homo copolymer and a block copolymer, wherein the copolymer contains carboxylic, amino, sulfonic, phosphonic or phosphenic functionalities, said polymer solution having a pH between 6.5 and 7.8, an osmolarity value between 250 and 600 mOsmL, and a polymer concentration of 0.5 to 3.0 w/v, and furtherwherein the polymer composition is admixed with blood or a component thereof prior to injecting the composition in the tissue of the patient in need of repairing or regeneration and is converted into a non-liquid state in time or upon heating.

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