SYSTEM FOR FORMING AN ARRAY OF EMULSIONS
First Claim
1. A system for forming an array of emulsions in parallel, comprising:
- a plate providing an array of emulsion production units each configured to produce a separate emulsion and each including a set of wells interconnected by channels that intersect to form a site of droplet generation, each set of wells includingat least one first input well to receive a continuous phase,a second input well to receive a dispersed phase, andan output well configured to receive from the site of droplet generation an emulsion of droplets of the dispersed phase disposed in the continuous phase.
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Accused Products
Abstract
A system, including method and apparatus, for forming an array of emulsions. The system may include a plate providing an array of emulsion production units each configured to produce a separate emulsion and each including a set of wells interconnected by channels that intersect to form a site of droplet generation. Each set of wells, in turn, may include (1) at least one first input well to receive a continuous phase, (2) a second input well to receive a dispersed phase, and (3) an output well configured to receive from the site of droplet generation an emulsion of droplets of the dispersed phase disposed in the continuous phase.
285 Citations
24 Claims
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1. A system for forming an array of emulsions in parallel, comprising:
a plate providing an array of emulsion production units each configured to produce a separate emulsion and each including a set of wells interconnected by channels that intersect to form a site of droplet generation, each set of wells including at least one first input well to receive a continuous phase, a second input well to receive a dispersed phase, and an output well configured to receive from the site of droplet generation an emulsion of droplets of the dispersed phase disposed in the continuous phase. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A system for forming an array of emulsions in parallel, comprising:
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a plate having an upper member attached to a lower member to form an array of emulsion production units each configured to produce a separate emulsion, each unit including a set of wells interconnected by channels that intersect to form a site of droplet generation, each set of wells including at least one first input well to receive a continuous phase, a second input well to receive a dispersed phase, and an output well configured to receive from the site of droplet generation an emulsion including droplets of the dispersed phase disposed in the continuous phase, wherein the lower member has an upper surface that is flat and that abuts a lower surface of the upper member to form a bottom wall of openings formed in the lower surface and corresponding to the wells and the channels of each unit. - View Dependent Claims (21)
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22. A method of forming an array of emulsions, comprising:
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selecting a plate including an array of emulsion production units each configured to produce a separate emulsion and each including a set of wells interconnected by channels that intersect to form a site of droplet generation, each set of wells including at least one first input well to receive a continuous phase, a second input well to receive a dispersed phase, and an output well configured to receive from the site of droplet generation an emulsion of droplets of the dispersed phase disposed in the continuous phase; and producing emulsions with the units. - View Dependent Claims (23, 24)
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Specification