Pyrrolo[2,3-b]pyridin-4-yl-amines and pyrrolo[2,3-b]pyrimidin-5-yl-amines as janus kinase inhibitors
3 Assignments
0 Petitions
Accused Products
Abstract
The present invention provides pyrrolo[2,3-b]pyridine-4-yl amines pyrrolo[2,3-b]pyrimidin-4-yl amines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases and cancer.
-
Citations
69 Claims
-
1-33. -33. (canceled)
-
34. A method of inhibiting an activity of JAK comprising contacting said JAK with a compound of Formula I:
-
35-40. -40. (canceled)
- 41. A method of treating a disease in a patient, wherein said disease is associated with JAK activity, comprising administering to said patient a therapeutically effective amount of a compound of Formula I:
-
50-54. -54. (canceled)
- 55. A method of treating a skin disorder in a patient comprising topically administering to said patient a therapeutically effective amount of a compound of Formula II:
- 61. A method of treating cancer in a patient comprising administering to said patient a therapeutically effective amount of a compound of Formula I:
Specification