OCULAR PRESSURE REGULATION

• US 20110087149A1
• Filed: 12/17/2010
• Published: 04/14/2011
• Est. Priority Date: 11/14/2003
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Transcend Medical Incorporated (Alcon Incorporated)
• Inventors: Theodore Coroneo, Minas
• Granted Patent: US 8,771,218 B2
• Time in Patent Office: Days
• US Class Current: 604/8
• CPC Class Codes: A61F 2/148 Implantation instruments specially adapted therefor
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

Disclosed are devices and methods of treating an ocular disorder including forming a self-sealing incision in a cornea into an anterior chamber of an eye; introducing through the incision a fluid drainage tube having a distal end, a proximal end and a longitudinal, internal lumen extending through the fluid drainage tube, wherein at least the proximal end passes through the anterior chamber; and implanting the distal end of the fluid drainage tube in fluid communication with the suprachoroidal space such that the proximal end of the fluid drainage tube remains in fluid communication with the anterior chamber.

Claims

1. A method of treating an ocular disorder, comprising:

forming a self-sealing incision in a cornea into the anterior chamber of an eye;

introducing through the incision an ophthalmic implant having a distal end, a proximal end and a longitudinal, internal lumen extending through the ophthalmic implant, wherein at least the proximal end passes through the anterior chamber;

surgically creating a previously non-existing space in the eye by separating at least a portion of the ciliary body from at least a portion of the sclera from within the anterior chamber to form the space;

implanting the distal end of the ophthalmic implant in communication with the space; and

causing aqueous humour to flow through the internal lumen from the anterior chamber towards the space.

2. A method as in claim 1, wherein the ophthalmic implant comprises a tube.

3. A method as in claim 1, wherein the space comprises at least a portion of the suprachoroidal space.

4. A method as in claim 1, wherein surgically creating a previously non-existing space in the eye comprises performing a cyclodialysis.

5. A method as in claim 4, wherein the cyclodialysis is performed using an ocular instrument separate from the ophthalmic implant.

6. A method as in claim 4, further comprising inserting viscoelastic to further form the space.

7. A method as in claim 6, wherein inserting the viscoelastic comprises inserting viscoelastic through an attachment between the ciliary body and the sclera.

8. A method as in claim 7, wherein inserting the viscoelastic comprises enlarging an area of detachment of the ciliary body from the sclera.

9. A method as in claim 8, wherein the space extends into the suprachoroidal space.

10. A method as in claim 1, wherein the proximal end of the ophthalmic implant remains in fluid communication with the anterior chamber.

11. A method as in claim 1, wherein introducing through the incision an ophthalmic implant comprises introducing the entire ophthalmic implant into the anterior chamber of the eye.

12. A method as in claim 11, wherein introducing the entire ophthalmic implant into the anterior chamber of the eye comprises passing the distal end and the proximal end of the ophthalmic implant through the cornea.

13. A method as in claim 1, wherein introducing through the incision an ophthalmic implant comprises placing the ophthalmic implant in the eye after surgically creating the space.

14. A method as in claim 1, further comprising applying laser energy to the trabecular meshwork of the eye during the procedure method provided herein.

15. A method as in claim 1, wherein forming a self-sealing incision is performed under direct visualization using a gonioscopy lens.

16. A method as in claim 1, wherein forming a self-sealing incision comprises creating a self-sealing incision in the cornea 180 degrees away from a planned insertion site of the ophthalmic implant in the eye.

17. A method as in claim 1, wherein the incision is formed in the limbus of the cornea.

18. A method as in claim 1, further comprising filling the anterior chamber with a viscoelastic substance.

19. A method as in claim 1, further comprising injecting a viscoelastic substance into the anterior chamber of the eye prior to introducing the ophthalmic implant through the self-sealing incision.

20. A method as in claim 1, wherein aqueous pressure of the eye is maintained at a pressure of not less than 10 mmHg.

21. A method of treating an ocular disorder, comprising:

forming a self-sealing incision in a cornea into the anterior chamber of an eye;

introducing through the incision an ophthalmic implant having a distal end, a proximal end and a longitudinal, internal lumen extending through the fluid drainage device, wherein at least the proximal end passes through the anterior chamber;

surgically creating a drainage pathway by separating at least a portion of the ciliary body from at least a portion of the sclera from within the anterior chamber forming a space and implanting the distal end of the ophthalmic implant into the space; and

controlling drainage of aqueous humour from the anterior chamber towards the space.

22. A method as in claim 21, wherein the ophthalmic implant comprises a tube.

23. A method as in claim 21, wherein the space comprises at least a portion of the suprachoroidal space.

24. A method as in claim 21, wherein surgically creating the drainage pathway in the eye comprises performing a cyclodialysis.

25. A method as in claim 24, wherein the cyclodialysis is performed using an ocular instrument separate from the ophthalmic implant.

26. A method as in claim 24, further comprising inserting viscoelastic to further form the space.

27. A method as in claim 26, wherein inserting the viscoelastic comprises inserting viscoelastic through an attachment between the ciliary body and the sclera.

28. A method as in claim 27, wherein inserting the viscoelastic comprises enlarging an area of detachment of the ciliary body from the sclera.

29. A method as in claim 28, wherein the space extends into the suprachoroidal space.

30. A method as in claim 21, wherein the proximal end of the ophthalmic implant remains in fluid communication with the anterior chamber.

31. A method as in claim 21, wherein introducing through the incision an ophthalmic implant comprises introducing the entire ophthalmic implant into the anterior chamber of the eye.

32. A method as in claim 31, wherein introducing the entire ophthalmic implant into the anterior chamber of the eye comprises passing the distal end and the proximal end of the ophthalmic implant through the cornea.

33. A method as in claim 21, wherein introducing through the incision an ophthalmic implant comprises placing the ophthalmic implant in the eye after surgically creating the drainage pathway.

34. A method as in claim 21, further comprising applying laser energy to the trabecular meshwork of the eye during the procedure method provided herein.

35. A method as in claim 21, wherein forming a self-sealing incision is performed under direct visualization using a gonioscopy lens.

36. A method as in claim 21, wherein forming a self-sealing incision comprises creating a self-sealing incision in the cornea 180 degrees away from a planned insertion site of the ophthalmic implant in the eye.

37. A method as in claim 21, wherein the incision is formed in the limbus of the cornea.

38. A method as in claim 21, further comprising filling the anterior chamber with a viscoelastic substance.

39. A method as in claim 21, further comprising injecting a viscoelastic substance into the anterior chamber of the eye prior to introducing the ophthalmic implant through the self-sealing incision.

40. A method as in claim 21, wherein aqueous pressure of the eye is maintained at a pressure of not less than 10 mmHg.