FLUIDIC TISSUE AUGMENTATION COMPOSITIONS AND METHODS
0 Assignments
0 Petitions
Accused Products
Abstract
Compositions and method for augmenting tissue after delivery to localized area. The compositions include a hydrogel and a dermal filler. The hydrogel can polymerize and/or crosslink upon a first trigger event. The dermal filler can also optionally crosslink upon a second trigger event.
-
Citations
89 Claims
-
1-35. -35. (canceled)
-
36. A method of repairing or augmenting soft tissue in a subject, the method comprising
a. injecting into a subject in need thereof a composition comprising a biodegradable, polymerizable macromer, the macromer comprising a water soluble polymer modified with one or more biodegradable moieties; - and
b. polymerizing the macromer to provide a hydrogel wherein the hydrogel to soft tissue have a normalized compliance ratio of from about 0.05 to about 3, thus repairing or augmenting the soft tissue. - View Dependent Claims (37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88)
- and
-
89. A method of repairing or augmenting soft tissue in a subject, the method comprising a. injecting into a subject in need thereof a composition comprising a biodegradable, polymerizable macromer, the macromer comprising a water soluble polymer modified with one or more biodegradable moieties;
- and b. polymerizing the macromer to provide a hydrogel, thus repairing or augmenting the soft tissue.
Specification