OCULAR IMPLANT DELIVERY SYSTEM AND METHODS THEREOF
First Claim
1. An ocular implant system, comprising:
- an ocular implant, the implant comprising an elongated body, the elongated body including;
an inlet port arranged on a proximal end segment of the implant to communicate with an anterior chamber of an eye;
an inner lumen communicating with the inlet port;
one or more outlet ports in communication with the inner lumen and configured to drain aqueous humor to a uveoscleral outflow pathway of the eye; and
one or more retention features arranged to contact ocular tissue; and
a delivery device comprising;
an elongated member carrying the ocular implant and being configured for ab interno insertion of the ocular implant, the elongated member having a distal portion, the distal portion being sufficiently flexible at least when deployed in an eye so as to bend when accessing a target tissue site in an anterior chamber angle within the eye with the elongated member extending through an opening into an anterior chamber of an eye disposed apart from the target tissue site, wherein the distal portion of the elongated member is further configured to make an opening through ocular tissue at the target tissue site.
3 Assignments
0 Petitions
Accused Products
Abstract
Systems and methods for treating ocular disorders are disclosed. One system has a delivery instrument, with a non-linear axis, configured to be inserted into an anterior chamber of an eye and moved to a location proximate a physiologic outflow pathway of the eye. The delivery instrument carries an implant that has a distal end sized for insertion into tissue such that aqueous humor drains from the anterior chamber to the physiologic outflow pathway. One method involves inserting a non-linear portion of a delivery device into the anterior chamber to position an implant within the eye. Another method involves using a delivery device with a curved distal portion to implant an implant at a location communicating with the physiologic outflow pathway. The delivery can be through a corneal incision and the implant can comprise a drug.
83 Citations
26 Claims
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1. An ocular implant system, comprising:
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an ocular implant, the implant comprising an elongated body, the elongated body including; an inlet port arranged on a proximal end segment of the implant to communicate with an anterior chamber of an eye; an inner lumen communicating with the inlet port; one or more outlet ports in communication with the inner lumen and configured to drain aqueous humor to a uveoscleral outflow pathway of the eye; and one or more retention features arranged to contact ocular tissue; and a delivery device comprising; an elongated member carrying the ocular implant and being configured for ab interno insertion of the ocular implant, the elongated member having a distal portion, the distal portion being sufficiently flexible at least when deployed in an eye so as to bend when accessing a target tissue site in an anterior chamber angle within the eye with the elongated member extending through an opening into an anterior chamber of an eye disposed apart from the target tissue site, wherein the distal portion of the elongated member is further configured to make an opening through ocular tissue at the target tissue site. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method of treating an ocular condition, the method comprising:
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providing an ocular implant comprising an elongated body including;
an inlet port on a proximal end segment of the implant to communicate with an anterior chamber of the eye, an inner lumen communicating with the inlet port, one or more retention features, and having one or more outlet ports in communication with the inner lumen and configured to drain aqueous humor to a uveoscleral outflow pathway of the eye; andforming a first opening to access an anterior chamber of an eye; inserting a delivery device carrying the ocular implant through the first opening, wherein the ocular implant is carried by a flexible distal portion of an elongate member of a delivery device; advancing the ocular implant into the anterior chamber and across an iris to an anterior chamber angle using the delivery device; forming an opening in ocular tissue at the anterior chamber angle using the distal portion of the delivery device, wherein the distal portion of the delivery device is sufficiently flexible so as to bend when accessing the ocular tissue at the anterior chamber angle; implanting the ocular implant into eye tissue through the formed opening in the anterior chamber angle; contacting ocular tissue with the one or more retention features to inhibit migration of the implant once implanted; and draining aqueous humor through the ocular implant from the inlet of the ocular implant, which resides in the anterior chamber, through the lumen and out an outlet port into a uveoscleral outflow pathway. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26)
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Specification