IONTOPHORETIC DEVICE WITH CONTACT SENSOR

• US 20110092881A1
• Filed: 10/13/2010
• Published: 04/21/2011
• Est. Priority Date: 05/08/2009
• Status: Abandoned Application

• Current Assignee: Iontera, Inc.
• Original Assignee: Isis Biopolymer, Inc.
• Inventors: Durand, Emma Amelia, Jordan, Michael K.
• Application Number:
  US12/903,924
• Publication Number:
  US 20110092881A1
• Time in Patent Office: Days
• US Class Current: 604/20
• CPC Class Codes: A61K 9/0009 involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis microelectromechanical systems A61K9/0097
• CPC Class Codes: A61N 1/0428 Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0444 Membrane
• CPC Class Codes: A61N 1/0448 Drug reservoir
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428

Abstract

The present application discloses an iontophoretic device with a contact electrode for detecting placement of the device and/or characteristics of the wearer'"'"'s tissue.

Claims

1. An iontophoretic device for delivering a drug into the tissue of a wearer, the device comprising:

a base;

a drug reservoir containing a supply of charged drug ions;

a driving electrode positioned above the drug reservoir;

a counterelectrode positioned below the drug reservoir opposite the driving electrode;

a control circuit including a power source, the control circuit being coupled to the driving electrode and the counterelectrode and operable in a driving mode for applying a potential to the driving electrode of the same polarity as the charge of the charged drug ions and a potential of opposite polarity to the counterelectrode so as to drive the charged drug ions towards the tissue of the wearer; and

a contact electrode on a bottom of the body for contact with the user'"'"'s tissue, the contact electrode being coupled to the controller for application of a potential of a polarity opposite the counterelectrode, the controller being configured to detect current flow through the wearer'"'"'s tissue between the contact electrode and the counterelectrode.

2. An iontophoretic device according to claim 1, wherein the control circuit is configured to permit the operation in the driving mode upon detecting the current flow through the wearer'"'"'s tissue between the contact electrode and the counterelectrode.

3. An iontophoretic device according to claim 1, wherein the control circuit includes a sensor for detecting a density of the current flow through the wearer'"'"'s tissue between the contact electrode and the counterelectrode.

4. An iontophoretic device according to claim 3, wherein the control circuit is configured to adjust a density of current flow between the driving electrode and the counterelectrode based on sensor'"'"'s detection of the density of current flow through the wearer'"'"'s tissue between the contact electrode and the counterelectrode.

5. An iontophoretic device according to claim 1, further comprising a light indicator, said control circuit being coupled to the light indicator and configured to activate the light indicator to emit an activation signal in the driving mode.

6. An iontophoretic device according to claim 5, wherein said light indicator is an LED.

7. An iontophoretic device for delivering a drug into the tissue of a wearer, the device comprising:

a base;

a drug reservoir containing a supply of charged drug ions;

a plurality of electrodes including a driving electrode positioned above the drug reservoir and a counterelectrode;

a control circuit including a power source, the control circuit being coupled to the driving electrode and the counterelectrode and operable in a driving mode for applying a potential to the driving electrode of the same polarity as the charge of the charged drug ions and a potential of opposite polarity to the counterelectrode so as to drive the charged drug ions towards the tissue of the wearer; and

a contact electrode on a bottom of the body for contact with the user'"'"'s tissue, the contact electrode being coupled to the controller for application of a potential, the controller being configured to detect current flow through the wearer'"'"'s tissue between the contact electrode and at least one of the plurality of electrodes;

wherein the control circuit includes a sensor for detecting a parameter of the current flow through the wearer'"'"'s tissue between the contact electrode and the at least one of the plurality of electrodes;

wherein the control circuit is configured to adjust a parameter of current flow and/or the potential difference between the driving electrode and the counterelectrode based on sensor'"'"'s detection of the parameter of current flow through the wearer'"'"'s tissue between the contact electrode and the at least one of the plurality of electrodes.

8. An iontophoretic device according to claim 7, wherein the parameter of the current flow detected by the sensor is current density.

9. An iontophoretic device according to claim 7, wherein the parameter of the current flow adjusted by the control circuit is the current density.

10. An iontophoretic device according to claim 8, wherein the parameter of the current flow adjusted by the control circuit is the current density.