ELECTRICAL STIMULATION THERAPY USING DECAYING CURRENT PULSES

• US 20110093041A1
• Filed: 10/21/2009
• Published: 04/21/2011
• Est. Priority Date: 10/21/2009
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Straka, Scott E., Torgerson, Nathan A.
• Granted Patent: US 9,259,571 B2
• Time in Patent Office: Days
• US Class Current: 607/59
• CPC Class Codes: A61N 1/00 Electrotherapy; Circuits therefor A61N2/00 takes precedence; irradiation apparatus A61N5/00
• CPC Class Codes: A61N 1/08 Arrangements or circuits for monitoring, protecting, controlling or indicating for external stimulators A61N1/3603; for implantable neurostimulators A61N1/36128; for heart stimulators A61N1/37; for defibrillators A61N1/3925
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components

Abstract

This disclosure describes generation of electrical stimulation pulses for electrical stimulation therapy. The stimulation pulses have a pulse current level and pulse width, and may be generated by a current regulator. The pulse voltage level may be a voltage level delivered by the current regulator while maintaining regulation of the pulse current level. During delivery of a pulse, a supply voltage level may decrease due to discharging of a supply capacitance, and the pulse voltage level may increase due to charging of a load capacitance. The pulse current level may be controlled to decrease during the pulse width such that a sum of the pulse voltage level and a headroom voltage of the current regulator does not exceed the supply voltage level. In some examples, the pulse may include sub-pulses with different sub-pulse current levels, where an earlier sub-pulse has a higher pulse current level than a later sub-pulse.

Claims

1. A method for delivery of electrical stimulation, the method comprising:

generating, with a current regulator, an electrical stimulation pulse having a pulse current level, a pulse voltage level, and a pulse width;

controlling the pulse current level to decrease during the pulse width such that a sum of the pulse voltage level and a headroom voltage level of the current regulator does not exceed a supply voltage level; and

delivering the pulse via one or more implantable electrodes.

2. The method of claim 1, wherein controlling comprises controlling the pulse current level to decrease based at least in part on a decrease in the supply voltage level during the pulse width.

3. The method of claim 2, wherein controlling comprises controlling the pulse current level to decrease based at least in part on the decrease in the supply voltage level and an increase in a load voltage during the pulse width.

4. The method of claim 1, wherein generating an electrical stimulation pulse comprises generating an electrical stimulation pulse having first and second sub-pulses, the second sub-pulse following the first sub-pulse in time, wherein the pulse current level of the second sub-pulse is less than the pulse current level of the first sub-pulse.

5. The method of claim 4, wherein an average of the pulse current level during the first and second sub-pulses is selected such that the sum of the pulse voltage level and the headroom voltage level does not exceed the supply voltage level.

6. The method of claim 4, wherein the first and second sub-pulses have equal sub-pulse widths.

7. The method of claim 6, wherein the first and second sub-pulses have unequal sub-pulse widths.

8. The method of claim 1, wherein the pulse voltage level increases during the pulse width and the supply voltage level decreases during the pulse width.

9. The method of claim 1, wherein generating comprises generating a plurality of pulses.

10. The method of claim 1, wherein controlling comprises controlling the pulse current level according to data stored in memory of at least one of an implantable medical device comprising the current regulator or an external programmer that communicates with the implantable medical device.

11. A medical device for delivery of electrical stimulation, the device comprising:

a stimulation pulse generator comprising a current regulator configured to generate an electrical stimulation pulse having a pulse current level, a pulse voltage level, and a pulse width;

a controller configured to control the pulse current level to decrease during the pulse width such that a sum of the pulse voltage level and a headroom voltage level of the current regulator does not exceed a supply voltage level; and

one or more implantable electrodes configured to deliver the pulse.

12. The device of claim 11, wherein the controller is configured to control the pulse current level to decrease based at least in part on a decrease in the supply voltage level during the pulse width.

13. The device of claim 12, wherein the controller is configured to control the pulse current level to decrease based at least in part on the decrease in the supply voltage level and an increase in a load voltage during the pulse width.

14. The device of claim 11, wherein the stimulation pulse generator is configured to generate the electrical stimulation pulse to have first and second sub-pulses, the second sub-pulse following the first sub-pulse in time, wherein the pulse current level of the second sub-pulse is less than the pulse current level of the first sub-pulse.

15. The device of claim 14, wherein an average of the pulse current level during the first and second sub-pulses is selected such that the sum of the pulse voltage level and the headroom voltage level does not exceed the supply voltage level.

16. The device of claim 14, wherein the first and second sub-pulses have equal sub-pulse widths.

17. The device of claim 14, wherein the first and second sub-pulses have unequal sub-pulse widths.

18. The device of claim 11, wherein the pulse voltage level increases during the pulse width and the supply voltage level decreases during the pulse width.

19. The device of claim 11, wherein the stimulation pulse generator is configured to generate a plurality of pulses.

20. The device of claim 11, wherein the controller is configured to control the pulse current level according to data stored in memory of at least one of the medical device or an external programmer that communicates with the medical device.

21. A medical device for delivery of electrical stimulation, the device comprising:

means for generating an electrical stimulation pulse having a pulse current level, a pulse voltage level, and a pulse width

means for controlling the pulse current level to decrease during the pulse width such that a sum of the pulse voltage level and a headroom voltage level of the generating

means does not exceed a supply voltage level; and

means for delivering the pulse via one or more implantable electrodes.

22. The device of claim 21, wherein the means for controlling comprises means for controlling the pulse current level to decrease based at least in part on a decrease in the supply voltage level during the pulse width.

23. The device of claim 22, wherein the means for controlling comprises means for controlling the pulse current level to decrease based at least in part on the decrease in the supply voltage level and an increase in a load voltage during the pulse width.

24. The device of claim 21, wherein the means for generating an electrical stimulation pulse comprises means for generating an electrical stimulation pulse having first and second sub-pulses, the second sub-pulse following the first sub-pulse in time, wherein the pulse current level of the second sub-pulse is less than the pulse current level of the first sub-pulse.

25. The device of claim 24, wherein an average of the pulse current level during the first and second sub-pulses is selected such that the sum of the pulse voltage level and the headroom voltage level does not exceed the supply voltage level.

26. The device of claim 24, wherein the first and second sub-pulses have equal sub-pulse widths.

27. The device of claim 24, wherein the first and second sub-pulses have unequal sub-pulse widths.

28. The device of claim 21, wherein the pulse voltage level increases during the pulse width and the supply voltage level decreases during the pulse width.

29. The device of claim 21, wherein the means for generating comprise means for generating a plurality of pulses.

30. The device of claim 21, wherein the means for controlling comprises means for controlling the pulse current level according to data stored in memory of at least one of an implantable medical device comprising the current regulator or an external programmer that communicates with the implantable medical device.