SYSTEM FOR ANIMAL HEALTH DIAGNOSIS

• US 20110093298A1
• Filed: 11/30/2010
• Published: 04/21/2011
• Est. Priority Date: 10/15/1999
• Status: Active Grant

• Current Assignee: Hemopet
• Original Assignee: Hemopet
• Inventors: Dodds, W. Jean
• Granted Patent: US 8,234,099 B2
• Time in Patent Office: Days
• US Class Current: 705/3
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: G16B 20/00 ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
• CPC Class Codes: G16B 20/20 Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
• CPC Class Codes: G16B 50/00 ICT programming tools or database systems specially adapted for bioinformatics
• CPC Class Codes: G16B 50/30 Data warehousing; Computing architectures
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/60 relating to nutrition control, e.g. diets
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 70/00 ICT specially adapted for the handling or processing of medical references
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
• CPC Class Codes: Y10S 128/92 Computer assisted medical diagnostics
• CPC Class Codes: Y10S 128/921 Diet management
• CPC Class Codes: Y10S 128/923 by comparison of patient data to other data

Abstract

Selecting the nutrition for an animal or animal group comprises performing a diagnostic test to obtain first data. A data base that comprises first data relating a genomic analysis of a bodily fluid or tissue sample from an animal to a physiological condition and optionally the genotype of the animal is accessed. A data base that comprises second data relating to effects of nutrition on genomic analysis is accessed. The first and second data are processed with input data defining the physiological condition and optionally the genotype of the animal or animal group to derive the nutrition for an animal or animal group.

Claims

1-39. -39. (canceled)

40. A method of selecting nutrition for a companion animal comprising:

accessing at least one database that comprises first data relating genetic descriptor genomic data to a physiological condition, wherein the genetic descriptor data is obtained from either a bodily fluid or tissue sample;

accessing second data comprising the effect of nutrition on the expression of a genetic descriptor of the genomic data;

analyzing by use of a computer the first and second data relating the effect of nutrition on the expression of the genetic descriptor of the genomic data thereby to address the physiological data, and

selecting a nutritional diet based on the processed data.

41. The method of claim 40 wherein the animal is defined by a characteristic selected from the group consisting of one or more characteristics of breed type, specific breed, chronological age, physiological age, activity level, state of health or state of disease or disorder.

42. The method of claim 40 wherein the first data are derived from samples collected from a group of animals representative of a range of genotypes and physiological conditions.

43. The method of claim 42 wherein the data is selected from the group consisting of breed, breed(s) of parents, pedigree, sex, age, and presence or absence of hereditary conditions and disorders.

44. The method of claim 42 wherein the data is selected from the group consisting of age, weight, veterinary medical history, reproductive history, present health, disorder or disease state, activity level, temperament and presence or absence of behavioral abnormalities.

45. The method of claim 42 wherein the first data comprises information obtained from DNA fingerprinting, PCR, RFLP, sequence-specific primer (SSP), or PCR sequence specific oligonucleotide (SSO) analysis.

46. The method of claim 40 wherein the first data comprises information obtained from DNA fingerprinting, PCR, RFLP, sequence-specific primer (SSP), or PCR sequence specific oligonucleotide (SSO) analysis.

47. A method as claimed in claim 40 wherein formulating the diet further comprises nutrition based on dietary modification.

48. A method as claimed in claim 43 further comprising obtaining the genotype by DNA mapping or genomic mapping.

49. The method as claimed in claim 40 wherein the physiological data comprises the gastrointestinal function, and the gastrointestinal function is assessed by serum chemistry, serum cobalamin, folate;

or trypsin-like immunoreactivity (TLI).

50. The method as claimed in claim 40 wherein the physiological function comprises the immunological function, and the immunological function is assessed by serum electrophoresis;

immunoglobulin levels;

complement levels;

urine electrophoresis;

leukocyte markers, cytokines, monokines or chemokine levels.

51. A method of selecting nutrition based on diagnosing a state of wellness, disease or physiological disorder, or a predisposition to disease or physiological disorder in a companion animal, comprising performing a diagnostic test to obtain first data, and (a) accessing a data base that comprises phenotype and genotype data storing animal information;

and (b) analyzing by use of a computer, the first data, genetic descriptor genomic data for the animal and temperament, longevity or cancer of the animal, and selecting the nutrition based on the diagnosis.

52. The method of claim 51 wherein the animal is defined by a characteristic selected from the group consisting of one or more characteristics of breed type, specific breed, chronological age, physiological age, activity level, state of health or state of disease or disorder.

53. The method of claim 51 wherein the first data are derived from samples collected from a group of animals representative of a range of genotypes and physiological conditions.

54. The method of claim 53 wherein the data is selected from the group consisting of breed, breed(s) of parents, pedigree, sex, age, and presence or absence of hereditary conditions and disorders.

55. The method of claim 53 wherein the data is selected from the group consisting of age, weight, veterinary medical history, reproductive history, present health, disorder or disease state, activity level, temperament and presence or absence of, behavioral abnormalities.

56. The method of claim 53 wherein the first data comprises information obtained from DNA fingerprinting, PCR, RFLP, sequence-specific primer (SSP), or PCR sequence specific oligonucleotide (SSO) analysis.

57. The method of claim 51 wherein the first data comprises information obtained from DNA fingerprinting, PCR, RFLP, sequence-specific primer (SSP), or PCR sequence specific oligonucleotide (SSO) analysis.

58. A method as claimed in claim 51 wherein formulating the diet further comprises nutrition based on dietary modification.

59. A method as claimed in claim 53 further comprising obtaining the genotype by DNA mapping or genomic mapping.

60. The method as claimed in claim 51 wherein gastrointestinal function is assessed by serum chemistry, serum cobalamin, folate;

or trypsin-like immunoreactivity (TLI).

61. The method as claimed in claim 51 wherein immunological function is assessed by serum electrophoresis;

immunoglobulin levels;

complement levels;

urine electrophoresis;

leukocyte markers, cytokines, monokines or chemokine levels.

62. A computer-readable physical medium having stored thereon instructions for a computer to access the medium comprising:

instructions to access data on the medium;

a first database on the medium related to the genetic descriptor genomic data of a companion animal;

a second database on the medium related to phenotypic data of the companion animal;

instructions to analyze the first and second database;

the analysis being based on data relating to the phenotypic data and genomic data; and

the analysis including a diagnosis of the nutritional needs of the selected animal and on the genetic descriptors of gastrointestinal function gastrointestinal function, immunological function, temperament, longevity or cancer of the animal, the selected animal being at least one of a selected animal family, selected animal breed, selected animal grouping, or selected animal species thereby to address the gastrointestinal function, immunological function, temperament, longevity or cancer of the animal.