DEVICES AND METHODS FOR ENDOLUMENAL WEIGHT LOSS TREATMENTS

• US 20110098725A1
• Filed: 09/03/2010
• Published: 04/28/2011
• Est. Priority Date: 09/03/2009
• Status: Abandoned Application

• Current Assignee: USGI Medical, Inc.
• Original Assignee: USGI Medical, Inc.
• Inventors: COX, John A., MAAHS, Tracy D., WHITE, James
• Application Number:
  US12/876,029
• Publication Number:
  US 20110098725A1
• Time in Patent Office: Days
• US Class Current: 606/139
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 17/0469 Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/0482 Needle or suture guides guides for drills, pins or wire A61B17/17; for puncturing needles A61B17/3403
• CPC Class Codes: A61B 17/0487 Suture clamps, clips or locks, e.g. for replacing suture knots; Instruments for applying or removing suture clamps, clips or locks suture anchors A61B17/0401; wound clamps or clips A61B17/08; ligaturing clamps or clips A61B17/122
• CPC Class Codes: A61B 2017/00296 mounted on an endoscope
• CPC Class Codes: A61B 2017/00349 Needle-like instruments having hook or barb-like gripping means, e.g. for grasping suture or tissue A61B17/06066 takes precedence
• CPC Class Codes: A61B 2017/00818 Treatment of the gastro-intestinal system
• CPC Class Codes: A61B 2017/0404 Buttons
• CPC Class Codes: A61B 2017/0409 Instruments for applying suture anchors
• CPC Class Codes: A61B 2017/0419 H-fasteners
• CPC Class Codes: A61B 2017/0464 for soft tissue
• CPC Class Codes: A61B 2017/0496 for tensioning sutures
• CPC Class Codes: A61B 2017/06052 Needle-suture combinations in which a suture is extending inside a hollow tubular needle, e.g. over the entire length of the needle
• CPC Class Codes: A61F 5/0086 using clamps, folding means or the like

Abstract

Devices and methods for forming and securing tissue folds, elongated invaginations, and tissue appositions in stomach tissue are used as a treatment for obesity. In a first embodiment, a plurality of tissue folds is formed in the fundus region of the stomach. In a second embodiment, one or more elongated invaginations are formed in the body region and/or antrum of the stomach. In a third embodiment, a plurality of tissue folds is formed in the fundus region of the stomach and one or more elongated invaginations is formed in the body region and/or antrum of the stomach. In other embodiments, a plurality of tissue folds is formed in the fundus region of the stomach and one or more tissue appositions are formed in the body region and/or antrum of the stomach. Additional embodiments include various combinations of tissue folds, elongated invaginations, tissue appositions, and other reconfigurations of stomach tissue.

Claims

1. An endolumenal treatment method, comprising:

advancing a tissue fastener deployment mechanism through a patient'"'"'s mouth and esophagus and into the patient'"'"'s stomach, the tissue fastener deployment mechanism including a first tissue fastener;

forming a first tissue fold in the tissue of the stomach fundus;

deploying the first tissue fastener from the tissue fastener deployment mechanism to thereby secure the first tissue fold;

securing a first plurality of additional tissue folds in the tissue of the stomach fundus;

approximating a first portion of tissue from a first location within the stomach and a second portion of tissue from a second location within the stomach; and

securing the first portion of tissue to the second portion of tissue to thereby form a first tissue apposition.

2. The endolumenal treatment method of claim 1, wherein the first portion of tissue is located substantially on the anterior wall of the stomach body region.

3. The endolumenal treatment method of claim 2, wherein the second portion of tissue is located substantially on the lateral wall of the stomach body region.

4. The endolumenal treatment method of claim 2, wherein the second portion of tissue is located substantially on the posterior wall of the stomach body region.

5. The endolumenal treatment method of claim 2, wherein the second portion of tissue is located substantially on the anterior wall of the stomach body region.

6. The endolumenal treatment method of claim 1, wherein the first portion of tissue is located substantially on the posterior wall of the stomach body region.

7. The endolumenal treatment method of claim 6, wherein the second portion of tissue is located substantially on the lateral wall of the stomach body region.

8. The endolumenal treatment method of claim 6, wherein the second portion of tissue is located substantially on the posterior wall of the stomach body region.

9. The endolumenal treatment method of claim 1, wherein the first portion of tissue is located substantially on the lateral wall of the stomach body region.

10. The endolumenal treatment method of claim 9, wherein the second portion of tissue is located substantially on the lateral wall of the stomach body region.

11. The endolumenal treatment method of claim 1, wherein the first tissue apposition comprises a first elongated invagination and a second elongated invagination that are approximated to define a gastric sleeve.

12. The endolumenal treatment method of claim 1, further comprising the step of forming a plurality of additional tissue appositions.

13. The endolumenal treatment method of claim 12, wherein the first tissue apposition and the plurality of additional tissue appositions define a generally staggered pattern located inferior to the opening of the patient'"'"'s esophagus.

14. The endolumenal treatment method of claim 12, wherein the first tissue apposition and the plurality of additional tissue appositions are located at substantially random locations in the stomach.

15. The endolumenal treatment method of claim 1, wherein the step of securing a first plurality of additional tissue folds in the tissue of the stomach fundus comprises securing a sufficient number of additional tissue folds to reconfigure the fundus such that at least about 50% of the internal fundus tissue surface does not extend substantially superior to the gastroesophageal junction (GEJ).

16. The endolumenal treatment method of claim 1, wherein the step of securing a first plurality of additional tissue folds in the tissue of the stomach fundus comprises securing a sufficient number of additional tissue folds to reconfigure the fundus such that at least about 75% of the internal fundus tissue surface does not extend substantially superior to the gastroesophageal junction (GEJ).

17. The endolumenal treatment method of claim 1, wherein the step of securing a first plurality of additional tissue folds in the tissue of the stomach fundus comprises securing a sufficient number of additional tissue folds to reconfigure the fundus such that substantially all of the internal fundus tissue surface does not extend substantially superior to the gastroesophageal junction (GEJ).

18. The endolumenal treatment method of claim 1, wherein the step of securing a first plurality of additional tissue folds in the tissue of the stomach fundus comprises securing a sufficient number of additional tissue folds to reconfigure the fundus such that the tissue of the stomach fundus is at least 50% effaced.

19. The endolumenal treatment method of claim 1, wherein the step of securing a first plurality of additional tissue folds in the tissue of the stomach fundus comprises securing a sufficient number of additional tissue folds to reconfigure the fundus such that the tissue of the stomach fundus is at least 75% effaced.

20. The endolumenal treatment method of claim 1, wherein the step of securing a first plurality of additional tissue folds in the tissue of the stomach fundus comprises securing a sufficient number of additional tissue folds to reconfigure the fundus such that the tissue of the stomach fundus is substantially completely effaced.