MULTIPLE VECTOR FLUID LOCALIZATION
First Claim
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1. An apparatus comprising:
- a first interface, configured to be coupled to implantable first electrodes configured to define a first measurement vector, within a subject, comprising a first excitation vector for providing a first excitation signal and a first response vector for sensing a first response to the first excitation signal;
a second interface, configured to be coupled to implantable second electrodes configured to define a second measurement vector, within the subject, comprising a second excitation vector for providing a second excitation signal and a second response vector for sensing a second response to the second excitation signal, wherein the second excitation vector is substantially orthogonal to the second response vector;
a tissue characteristic measurement circuit, selectively communicatively coupled to the first and second electrodes, and configured to repeatedly perform a first tissue characteristic measurement using the first measurement vector and to perform a second tissue characteristic measurement using the second measurement vector; and
a processor, communicatively coupled to the tissue characteristic measurement circuit, the processor configured to use information about a change in the first tissue characteristic measurement over a period of time and information about a change in the second tissue characteristic measurement over the period of time to provide an indication associated with how much fluid is present at an first location in the subject relative to how much fluid is present at a second location in the subject.
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Abstract
A differential or relative measurement between an orthogonal measurement vector and another measurement vector can be used to determine the location where fluid accumulation is occurring or the local change in such fluid accumulation. This can help diagnose or treat infection or hematoma or seroma at a pocket of an implanted cardiac rhythm management device, other implanted medical device, or prosthesis. It can also help diagnose or treat pulmonary edema, pneumonia, pulmonary congestion, pericardial effusion, pericarditis, pleural effusion, hemodilution, or another physiological condition.
40 Citations
20 Claims
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1. An apparatus comprising:
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a first interface, configured to be coupled to implantable first electrodes configured to define a first measurement vector, within a subject, comprising a first excitation vector for providing a first excitation signal and a first response vector for sensing a first response to the first excitation signal; a second interface, configured to be coupled to implantable second electrodes configured to define a second measurement vector, within the subject, comprising a second excitation vector for providing a second excitation signal and a second response vector for sensing a second response to the second excitation signal, wherein the second excitation vector is substantially orthogonal to the second response vector; a tissue characteristic measurement circuit, selectively communicatively coupled to the first and second electrodes, and configured to repeatedly perform a first tissue characteristic measurement using the first measurement vector and to perform a second tissue characteristic measurement using the second measurement vector; and a processor, communicatively coupled to the tissue characteristic measurement circuit, the processor configured to use information about a change in the first tissue characteristic measurement over a period of time and information about a change in the second tissue characteristic measurement over the period of time to provide an indication associated with how much fluid is present at an first location in the subject relative to how much fluid is present at a second location in the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method comprising:
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providing a first measurement vector, within a subject, comprising a first excitation vector for providing a first excitation signal and a first response vector for sensing a first response to the first excitation signal; providing a second measurement vector, within the subject, comprising a second excitation vector for providing a second excitation signal and a second response vector for sensing a second response to the second excitation signal, wherein the second excitation vector is substantially orthogonal to the second response vector; repeatedly performing a first tissue characteristic measurement using the first measurement vector and to perform a second tissue characteristic measurement using the second measurement vector; and using information about a change in the first tissue characteristic measurement over a period of time and information about a change in the second tissue characteristic measurement over the period of time to provide an indication associated with how much fluid is present at an first location in the subject relative to how much fluid is present at a second location in the subject. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
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19. An apparatus comprising:
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means for providing a first measurement vector, within a subject, comprising a first excitation vector for providing a first excitation signal and a first response vector for sensing a first response to the first excitation signal; means for providing a second measurement vector, within the subject, comprising a second excitation vector for providing a second excitation signal and a second response vector for sensing a second response to the second excitation signal, wherein the second excitation vector is substantially orthogonal to the second response vector; means for repeatedly performing a first tissue characteristic measurement using the first measurement vector and to perform a second tissue characteristic measurement using the second measurement vector; and means for using information about a change in the first tissue characteristic measurement over a period of time and information about a change in the second tissue characteristic measurement over the period of time to provide an indication associated with how much fluid is present at an first location in the subject relative to how much fluid is present at a second location in the subject. - View Dependent Claims (20)
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Specification