CALIBRATION PROCEDURES AND DEVICES FOR INVESTIGATION BIOLOGICAL SYSTEMS

• US 20110104027A1
• Filed: 11/03/2010
• Published: 05/05/2011
• Est. Priority Date: 03/11/2002
• Status: Active Grant

• Current Assignee: Janusz Pawliszyn
• Original Assignee: Janusz Pawliszyn
• Inventors: PAWLISZYN, Janusz
• Granted Patent: US 8,114,660 B2
• Time in Patent Office: Days
• US Class Current: 422/527
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 17/3403 Needle locating or guiding means guides for suture needles A61B17/0482; guiding or tracking by nuclear magnetic resonance G01R33/285
• CPC Class Codes: G01N 1/405 by adsorption or absorption
• CPC Class Codes: G01N 2030/009 Extraction
• CPC Class Codes: G01N 2030/062 extracting sample from raw material
• CPC Class Codes: Y10S 436/807 Apparatus included in process claim, e.g. physical support structures
• CPC Class Codes: Y10T 436/255 including use of a solid sorbent, semipermeable membrane, or liquid extraction

Abstract

Use of calibrant in extraction phase is described for quantification of components of interest in samples in laboratory application as well as in on-site monitoring. This approach is particularly useful for in-vivo investigation of living system.

Claims

1. A liquid phase microextraction device for extracting components contained in a sample said device comprising a liquid extraction phase and a calibrant in said liquid extraction phase, said liquid extraction phase contained in a sheath.

2. The device as claimed in claim 1 wherein said sheath is a needle.

3. The device as claimed in claim 1 wherein said sheath is a porous hollow fiber membrane.