CYANINE COMPOUNDS AND THEIR APPLICATION AS QUENCHING COMPOUNDS
0 Assignments
0 Petitions
Accused Products
Abstract
The present invention provides methods and non-fluorescent carbocyanine quencher compounds having the general formula:
Wherein the A moiety is a substituted pyridinium, unsubstituted pyridinium, substituted quinolinium, unsubstituted quinolinium, substituted benzazolium, unsubstituted benzazolium, substituted indolinium, or substituted indolinium. The invention further provides luminescent donor molecule-quencher pairs and luminescent donor molecule-quencher-luminescent acceptor molecule conjugates wherein the quencher is a cyanine compound of the present invention. The energy transfer pairs are used to detect an analyte of interest in a sample.
90 Citations
14 Claims
- 1. A compound having formula:
Specification