DIFFUSE REFLECTANCE SPECTROSCOPY DEVICE FOR QUANTIFYING TISSUE ABSORPTION AND SCATTERING
First Claim
1. A diffuse reflectance spectroscopy system for quantifying light absorption and scattering in a tissue mass, the system comprising:
- an optical probe comprising at least one entity for emitting light that interacts with a tissue mass and then is remitted into a collecting entity, wherein the collecting entity comprises a detector comprising one or more photodiodes; and
a processing unit for converting collected light, via a Monte Carlo algorithm or a diffusion algorithm into absorption and scattering data.
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Accused Products
Abstract
A diffuse reflectance spectroscopy system for quantifying electromagnetic absorption and scattering in a tissue is provided. Also provided are optical probes and methods for imaging a tissue mass. In some embodiments, the methods include the steps of contacting a tissue mass with an optical probe, wherein the optical probe includes at least one entity for emitting light that interacts with a tissue mass and then is remitted to a collecting entity, for collecting the light that has interacted with the tissue mass, wherein the collecting entity comprises a detector comprising one or more photodiodes; measuring turbid spectral data of the tissue mass using the optical probe; converting the turbid spectral data to at least one of absorption and scattering spectral data via a Monte Carlo algorithm or a diffusion algorithm; and quantifying tissue compositions and scatterer size in a tissue mass using the at least one of absorption and scattering spectral data.
119 Citations
29 Claims
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1. A diffuse reflectance spectroscopy system for quantifying light absorption and scattering in a tissue mass, the system comprising:
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an optical probe comprising at least one entity for emitting light that interacts with a tissue mass and then is remitted into a collecting entity, wherein the collecting entity comprises a detector comprising one or more photodiodes; and a processing unit for converting collected light, via a Monte Carlo algorithm or a diffusion algorithm into absorption and scattering data. - View Dependent Claims (2, 3, 4, 6, 7, 10, 13, 14, 15)
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5. (canceled)
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8-9. -9. (canceled)
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11-12. -12. (canceled)
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16-17. -17. (canceled)
- 18. An optical probe comprising at least one entity for emitting light into a tissue mass and at least one collecting entity for collecting light that has interacted with a tissue mass, wherein the collecting entity comprises one or more photodiodes.
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22. (canceled)
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29-50. -50. (canceled)
Specification