Method and Apparatus for Detecting False Hypoglycemic Conditions
First Claim
Patent Images
1. A method, comprising:
- receiving a plurality of time spaced analyte related data monitored by an analyte sensor in fluid contact with an analyte during a first time period;
detecting when one or more of the received plurality of time spaced analyte related data crosses a predetermined analyte threshold level during the first time period;
receiving a plurality of time spaced temperature data during the first time period;
determining a rate of change of the received plurality of time spaced temperature data and detecting when the determined rate of change crosses a predetermined rate of temperature change; and
asserting a notification when the determined rate of change of the received plurality of the time spaced temperature data reaches the predetermined rate of temperature change and when the one or more of the received plurality of time spaced analyte related data reaches the predetermined threshold analyte level during the first time period.
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Abstract
Embodiments of the present disclosure include detecting a concurrent occurrence of a decrease in monitored analyte level and a corresponding decrease in monitored on-skin temperature, confirming a presence of an impending hypoglycemic condition, and asserting a notification corresponding to the confirmed impending hypoglycemic condition. Devices, methods, systems and kits incorporating the same are also provided.
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Citations
59 Claims
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1. A method, comprising:
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receiving a plurality of time spaced analyte related data monitored by an analyte sensor in fluid contact with an analyte during a first time period; detecting when one or more of the received plurality of time spaced analyte related data crosses a predetermined analyte threshold level during the first time period; receiving a plurality of time spaced temperature data during the first time period; determining a rate of change of the received plurality of time spaced temperature data and detecting when the determined rate of change crosses a predetermined rate of temperature change; and asserting a notification when the determined rate of change of the received plurality of the time spaced temperature data reaches the predetermined rate of temperature change and when the one or more of the received plurality of time spaced analyte related data reaches the predetermined threshold analyte level during the first time period. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method, comprising:
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receiving a plurality of time spaced analyte related data monitored by an analyte sensor in fluid contact with an analyte during a first time period; detecting when one or more of the received plurality of time spaced analyte related data crosses a predetermined analyte threshold level during the first time period; receiving a plurality of time spaced temperature data during the first time period; detecting when one or more of the time spaced temperature related data crosses a predetermined threshold temperature level during the first time period; and asserting a notification when the one or more of the received plurality of time spaced analyte related data reaches a predetermined threshold analyte level and when the one or more of the plurality of time spaced temperature related data reaches the predetermined temperature threshold level during the first time period. - View Dependent Claims (12, 13, 14, 15)
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16. A method, comprising:
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monitoring a variation in on-skin temperature in proximity to a transcutaneously positioned analyte sensor having at least a portion in fluid contact with an analyte during a monitoring time period; detecting the variation in the monitored temperature exceeding a predetermined threshold level; confirming a presence of a medically significant condition when the detected variation in the monitored temperature exceeds the predetermined threshold level; and asserting a notification associated with the medically significant condition when it is confirmed; wherein confirming the presence of the medically significant condition includes determining a variation in the monitored analyte level exceeding the predetermined threshold level based on comparing a slope indicative of the change in the monitored analyte level substantially to a slope indicative of the change in the monitored on-skin temperature variation.
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17. A method, comprising:
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detecting a concurrent occurrence of a decrease in monitored analyte level and a corresponding decrease in monitored on-skin temperature; confirming a presence of an impending hypoglycemic condition; and asserting a notification corresponding to the confirmed impending hypoglycemic condition. - View Dependent Claims (18, 19, 20)
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21. A method of confirming hypoglycemic condition in a patient, comprising:
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monitoring a directional change in glucose level based on data stream received from an analyte sensor during a monitoring time period; monitoring a directional change in a first physiological parameter during the monitoring time period; monitoring a directional change in a second physiological parameter during the monitoring time period; detecting an initialization of a hypoglycemic alarm based at least in part on the directional change of the monitored glucose level; and comparing the directional change in one or more of the first or the second physiological parameters relative to the directional change in the glucose level prior to the assertion of the hypoglycemic alarm. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. An apparatus, comprising:
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one or more processors; and a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to receive a plurality of time spaced analyte related data monitored by an analyte sensor in fluid contact with an analyte during a first time period, determine a rate of change of the received plurality of time spaced analyte related data, receive a plurality of time spaced temperature data during the first time period, determine a rate of change of the received plurality of time spaced temperature data, compare the determined rate of change of the received plurality of the time spaced temperature data to the predetermined threshold level when the determined rate of change of the received plurality of time spaced analyte related data exceeds a predetermined threshold level, and assert a notification when the determined rate of change of the received plurality of the time spaced temperature data exceeds the predetermined threshold level. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42)
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43. An apparatus, comprising:
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one or more processors; and a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to monitor a variation in on-skin temperature in proximity to a transcutaneously positioned analyte sensor having at least a portion in fluid contact with an analyte during a monitoring time period, detect the variation in the monitored temperature exceeding a predetermined threshold level, confirm a presence of a medically significant condition when the detected variation in the monitored temperature exceeds the predetermined threshold level, and assert a notification associated with the medically significant condition when it is confirmed; wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to determine a variation in the monitored analyte level exceeding the predetermined threshold level based on comparing a slope indicative of the change in the monitored analyte level substantially to a slope indicative of the change in the monitored on-skin temperature variation.
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44. An apparatus, comprising:
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one or more processors; and a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to detect a concurrent occurrence of a decrease in monitored analyte level and a corresponding decrease in monitored on-skin temperature, confirm a presence of an impending hypoglycemic condition, and assert a notification corresponding to the confirmed impending hypoglycemic condition. - View Dependent Claims (45, 46, 47)
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48. An apparatus, comprising:
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one or more processors; and a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to monitor a directional change in glucose level based on data stream received from an analyte sensor during a monitoring time period, monitor a directional change in a first physiological parameter during the monitoring time period, monitor a directional change in a second physiological parameter during the monitoring time period, detect an initialization of a hypoglycemic alarm based at least in part on the directional change of the monitored glucose level, and compare the directional change in one or more of the first or the second physiological parameters relative to the directional change in the glucose level prior to the assertion of the hypoglycemic alarm. - View Dependent Claims (49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59)
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Specification