Multi-lumen heat transfer catheter systems

• US 20110106051A1
• Filed: 10/08/2010
• Published: 05/05/2011
• Est. Priority Date: 08/13/1992
• Status: Active Grant

• Current Assignee: Vention Medical Advanced Components, Inc. (Nordson Corporation)
• Original Assignee: Advanced Polymers Incorporated
• Inventors: Saab, Mark A.
• Granted Patent: US 8,257,340 B2
• Time in Patent Office: Days
• US Class Current: 604/509
• CPC Class Codes: A61B 2018/00166 Multiple lumina
• CPC Class Codes: A61F 2007/0054 with a closed fluid circuit, e.g. hot water
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/123 using a flexible balloon containing the thermal element
• CPC Class Codes: A61M 2025/0025 having a collapsible lumen
• CPC Class Codes: A61M 2025/0031 characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment
• CPC Class Codes: A61M 2025/0034 characterized by elements which are assembled, connected or fused, e.g. splittable tubes, outer sheaths creating lumina or separate cores making of catheters A61M25/0009
• CPC Class Codes: A61M 2025/0036 with more than four lumina
• CPC Class Codes: A61M 2025/1031 Surface processing of balloon members, e.g. coating or deposition; Mounting additional parts onto the balloon member's surface
• CPC Class Codes: A61M 2025/1072 having balloons with two or more compartments
• CPC Class Codes: A61M 2025/1075 having a balloon composed of several layers, e.g. by coating or embedding
• CPC Class Codes: A61M 2025/1086 having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
• CPC Class Codes: A61M 25/0009 Making of catheters or other medical or surgical tubes
• CPC Class Codes: A61M 25/0029 characterized by features relating to least one lumen located at the middle part of the catheter, e.g. slots, flaps, valves, cuffs, apertures, notches, grooves or rapid exchange ports catheter shaft surface irregularities A61M2025/006
• CPC Class Codes: A61M 25/0032 characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
• CPC Class Codes: A61M 25/1027 Making of balloon catheters
• CPC Class Codes: A61M 25/1029 Production methods of the balloon members, e.g. blow-moulding, extruding, deposition or by wrapping a plurality of layers of balloon material around a mandril
• CPC Class Codes: A61M 25/104 used for angioplasty
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104

Abstract

Heat transfer catheter apparatus and methods of making and using same are disclosed wherein fluid connection means is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations.

Claims

1. Fluid circulation catheter apparatus comprising in combination:

an elongated inlet fluid lumen having proximal and distal ends, said inlet lumen being defined by inlet lumen wall means and having fluid inlet means proximate to said proximal end;

an elongated outlet fluid lumen having proximal and distal ends, said outlet lumen being defined by outlet lumen wall means and having fluid outlet means proximate to said proximal end; and

fluid connection means whereby substantially all fluid would pass directly from said inlet lumen to said outlet lumen.

2. Catheter apparatus according to claim 1 further comprising a fluid inside said inlet and outlet lumens, said fluid being maintained at a substantially constant temperature which is different from normal body temperature.

3. Catheter apparatus according to claim 1 further wherein said fluid connection means is located proximate to said distal ends of said inlet and outlet lumens.

4. Catheter apparatus according to claim 1 further comprising single-layer, integrally formed wall means comprising at least a portion of said inlet lumen wall means and at least a portion of said outlet lumen wall means, said integrally formed wall means separating the interior of said inlet lumen from the interior of said outlet lumen.

5. Catheter apparatus according to claim 4 wherein said fluid connection means comprises at least an aperture in said integrally formed wall means.

6-73. -73. (canceled)

74. A catheter system to transfer thermal energy to or away from an internal body location and/or a body fluid by heat transfer to or from a working fluid, the system comprising:

an inlet lumen; and

,

an outlet lumen, the outlet lumen coupled to the inlet lumen so as to transfer the working fluid between the two, the outlet lumen having a structure to induce turbulence in the body fluid or in the working fluid, and wherein the outlet lumen further comprises at least one shape or surface feature that induces turbulence in a working fluid passing through that lumen.

75. A method of changing the temperature of an internal body location and/or a body fluid, the method comprising the steps of:

providing an inflatable heat transfer element, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a turbulence-inducing shape;

inserting the inflatable heat transfer element into a vascular system;

delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid being different from that of the body fluid in the vascular system;

inflating the inflatable heat transfer element with the circulating working fluid;

inducing turbulence in the working fluid or in the body fluid by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the body fluid; and

,

returning the working fluid to the working fluid supply via the outlet lumen.

76. A method for treating a patient by providing heating or cooling at an internal body location and/or to a body fluid, the method comprising the steps of:

providing a catheter system comprising a catheter and a heating or cooling element attached to a distal end thereof, the heating or cooling element employing fluid mixing-inducing surface features;

inserting the catheter through the vascular system of the patient to place the heating or cooling element at a desired location along the vascular system;

circulating heat transfer fluid at a temperature different from that of the vascular system through the heating or cooling element; and

,

transferring heat between the heating or cooling element and the body fluid in the vascular system, whereby the body fluid is heated or cooled;

wherein the mixing-inducing surface features are configured to cause mixing in the heat transfer fluid circulating through the heating or cooling element and/or in the body fluid in the vascular system having the heating or cooling element.

77. A method for cooling a patient'"'"'s body intravascularly, the method comprising the steps of:

providing a catheter system comprising a catheter and a heating or cooling element attached to a distal end thereof, the heating or cooling element having a mixing-inducing shape and/or surface feature;

inserting the catheter through the vascular system of the patient to place the heating or cooling element at a desired location inside the patient;

circulating heat transfer fluid at a temperature different from that of the vascular system through the heating or cooling element including at least the element portion having the mixing-inducing shape and/or surface feature to create turbulence in the heat transfer fluid; and

,

transferring heat between the patient'"'"'s vascular system and the heating or cooling element.