Osmium Compound Useful as Redox Mediator

• US 20110108417A1
• Filed: 01/13/2011
• Published: 05/12/2011
• Est. Priority Date: 06/27/2006
• Status: Active Grant

• Current Assignee: Agamatrix Incorporated (AgaMatrix Holdings LLC d/b/a WaveForm Diabetes)
• Original Assignee: Agamatrix Incorporated (AgaMatrix Holdings LLC d/b/a WaveForm Diabetes)
• Inventors: Harding, Ian
• Granted Patent: US 8,207,336 B2
• Time in Patent Office: Days
• US Class Current: 204/403.04
• CPC Class Codes: C12Q 1/004 mediator-assisted
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/3271 Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001

Abstract

Bis-(4,4′dimethyl-2,2′bipyridyl) picolinate osmium complexes are useful as mediators in the electrochemical test strips, such as those used in the detection of glucose.

Claims

1. A compound of the formula

2. A compound of the formula

3. The compound of claim 2, wherein Y is Cl⁻

.

5. The improvement of claim 3, wherein the counterion is Cl⁻

4. In a disposable test strip for measurement of glucose in a blood sample, said test strip containing an enzyme that reacts with glucose and a redox mediator compound for regenerating enzyme, the improvement wherein the redox mediator comprises a compound of the formula