METHODS AND APPARATUS FOR THE PLANNING AND DELIVERY OF RADIATION TREATMENTS
First Claim
1. A method for planning delivery of radiation dose to a target region within a subject, the method comprising:
- iteratively optimizing a simulated dose distribution relative to a set of one or more optimization goals comprising a desired dose distribution in the subject over an initial plurality of control points along a trajectory which involves relative movement between a radiation source and the subject;
upon reaching one or more initial termination conditions;
specifying an increased plurality of control points along the trajectory, the increased plurality of control points comprising a larger number of control points than the initial plurality of control points; and
iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over the increased plurality of control points.
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Accused Products
Abstract
Methods and apparatus are provided for planning and delivering radiation treatments by modalities which involve moving a radiation source along a trajectory relative to a subject while delivering radiation to the subject. In some embodiments the radiation source is moved continuously along the trajectory while in some embodiments the radiation source is moved intermittently. Some embodiments involve the optimization of the radiation delivery plan to meet various optimization goals while meeting a number of constraints. For each of a number of control points along a trajectory, a radiation delivery plan may comprise: a set of motion axes parameters, a set of beam shape parameters and a beam intensity.
95 Citations
26 Claims
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1. A method for planning delivery of radiation dose to a target region within a subject, the method comprising:
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iteratively optimizing a simulated dose distribution relative to a set of one or more optimization goals comprising a desired dose distribution in the subject over an initial plurality of control points along a trajectory which involves relative movement between a radiation source and the subject; upon reaching one or more initial termination conditions; specifying an increased plurality of control points along the trajectory, the increased plurality of control points comprising a larger number of control points than the initial plurality of control points; and iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over the increased plurality of control points. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. A program product comprising computer readable instructions which, when executed by a processor, cause the processor to execute a method for planning delivery of radiation dose to a target region within a subject, the method comprising:
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iteratively optimizing a simulated dose distribution relative to a set of one or more optimization goals comprising a desired dose distribution in the subject over an initial plurality of control points along a trajectory which involves relative movement between a radiation source and the subject; upon reaching one or more initial termination conditions; specifying an increased plurality of control points along the trajectory, the increased plurality of control points comprising a larger number of control points than the initial plurality of control points; and iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over the increased plurality of control points.
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Specification