IN VITRO DETERMINATION OF ANALYTE LEVELS WITHIN BODY FLUIDS
First Claim
1. An apparatus for determining the level of an analyte in a biological fluid sample from a patient, the apparatus comprising:
- an analyte detection system configured to determine the level of at least one analyte in the biological fluid sample;
a sample extractor configured to withdraw the biological fluid sample through the skin of the patient;
a fluid separator configured to move at least a portion of the biological fluid sample while at the same time separating a first component of the biological fluid sample from other components thereof, wherein at least one of the other components would interfere with the measurement performed by the analyte detection system;
a sample element comprising a sample cell and a sample supply passage in fluid communication with the sample cell, the sample cell configured to;
receive at least a portion of the first component of the biological fluid sample through the sample supply passage; and
hold the portion of the first component of the biological fluid sample between a first sample cell wall and a second sample cell wall of the sample cell while the analyte detection system analyzes the portion of the first component of the biological fluid sample to determine the level of the at least one analyte in the biological fluid sample.
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Accused Products
Abstract
A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.
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Citations
16 Claims
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1. An apparatus for determining the level of an analyte in a biological fluid sample from a patient, the apparatus comprising:
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an analyte detection system configured to determine the level of at least one analyte in the biological fluid sample; a sample extractor configured to withdraw the biological fluid sample through the skin of the patient; a fluid separator configured to move at least a portion of the biological fluid sample while at the same time separating a first component of the biological fluid sample from other components thereof, wherein at least one of the other components would interfere with the measurement performed by the analyte detection system; a sample element comprising a sample cell and a sample supply passage in fluid communication with the sample cell, the sample cell configured to; receive at least a portion of the first component of the biological fluid sample through the sample supply passage; and hold the portion of the first component of the biological fluid sample between a first sample cell wall and a second sample cell wall of the sample cell while the analyte detection system analyzes the portion of the first component of the biological fluid sample to determine the level of the at least one analyte in the biological fluid sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for determining the level of an analyte in a biological fluid sample from a patient, the method comprising:
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providing an analyte detection system configured to determine the level of at least one analyte in the biological fluid sample; providing a disposable sample element configured to receive a portion of the biological fluid sample, the disposable sample element comprising a sample cell and a sample supply passage extending from and in fluid communication with the sample cell; analyzing a first biological fluid sample by; withdrawing the biological fluid sample from the patient; separating a first component of the biological fluid sample from other components thereof, wherein at least one of the other components would interfere with the measurement performed by the analyte detection system; causing at least a portion of the first component of the biological fluid sample to flow into the sample cell; holding the at least a portion of the first component of the biological fluid sample in the sample cell while the analyte detection system analyzes the at least a portion of the first component of the biological fluid sample to determine the level of the at least one analyte in the biological fluid sample; analyzing at least a second biological fluid sample using the disposable sample element by performing the same steps used to analyze the first biological fluid sample prior to removing and replacing the disposable sample element. - View Dependent Claims (13, 14, 15, 16)
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Specification